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Microvascular stabilization via blood-brain barrier regulation prevents seizure activity.
Greene C, Hanley N, Reschke CR, Reddy A, Mäe MA, Connolly R, Behan C, O'Keeffe E, Bolger I, Hudson N, Delaney C, Farrell MA, O'Brien DF, Cryan J, Brett FM, Beausang A, Betsholtz C, Henshall DC, Doherty CP, Campbell M. Greene C, et al. Among authors: betsholtz c. Nat Commun. 2022 Apr 14;13(1):2003. doi: 10.1038/s41467-022-29657-y. Nat Commun. 2022. PMID: 35422069 Free PMC article.
Pericytes regulate the blood-brain barrier.
Armulik A, Genové G, Mäe M, Nisancioglu MH, Wallgard E, Niaudet C, He L, Norlin J, Lindblom P, Strittmatter K, Johansson BR, Betsholtz C. Armulik A, et al. Among authors: betsholtz c. Nature. 2010 Nov 25;468(7323):557-61. doi: 10.1038/nature09522. Epub 2010 Oct 13. Nature. 2010. PMID: 20944627
Notch3 is necessary for blood vessel integrity in the central nervous system.
Henshall TL, Keller A, He L, Johansson BR, Wallgard E, Raschperger E, Mäe MA, Jin S, Betsholtz C, Lendahl U. Henshall TL, et al. Among authors: betsholtz c. Arterioscler Thromb Vasc Biol. 2015 Feb;35(2):409-20. doi: 10.1161/ATVBAHA.114.304849. Epub 2014 Dec 4. Arterioscler Thromb Vasc Biol. 2015. PMID: 25477343 Free article.
Gpr116 Receptor Regulates Distinctive Functions in Pneumocytes and Vascular Endothelium.
Niaudet C, Hofmann JJ, Mäe MA, Jung B, Gaengel K, Vanlandewijck M, Ekvärn E, Salvado MD, Mehlem A, Al Sayegh S, He L, Lebouvier T, Castro-Freire M, Katayama K, Hultenby K, Moessinger C, Tannenberg P, Cunha S, Pietras K, Laviña B, Hong J, Berg T, Betsholtz C. Niaudet C, et al. Among authors: betsholtz c. PLoS One. 2015 Sep 22;10(9):e0137949. doi: 10.1371/journal.pone.0137949. eCollection 2015. PLoS One. 2015. PMID: 26394398 Free PMC article.
VEGFR2 pY949 signalling regulates adherens junction integrity and metastatic spread.
Li X, Padhan N, Sjöström EO, Roche FP, Testini C, Honkura N, Sáinz-Jaspeado M, Gordon E, Bentley K, Philippides A, Tolmachev V, Dejana E, Stan RV, Vestweber D, Ballmer-Hofer K, Betsholtz C, Pietras K, Jansson L, Claesson-Welsh L. Li X, et al. Among authors: betsholtz c. Nat Commun. 2016 Mar 23;7:11017. doi: 10.1038/ncomms11017. Nat Commun. 2016. PMID: 27005951 Free PMC article.
Age-dependent modulation of vascular niches for haematopoietic stem cells.
Kusumbe AP, Ramasamy SK, Itkin T, Mäe MA, Langen UH, Betsholtz C, Lapidot T, Adams RH. Kusumbe AP, et al. Among authors: betsholtz c. Nature. 2016 Apr 21;532(7599):380-4. doi: 10.1038/nature17638. Epub 2016 Apr 13. Nature. 2016. PMID: 27074508 Free PMC article.
344 results