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Promiscuous recognition of MR1 drives self-reactive mucosal-associated invariant T cell responses.
Chancellor A, Alan Simmons R, Khanolkar RC, Nosi V, Beshirova A, Berloffa G, Colombo R, Karuppiah V, Pentier JM, Tubb V, Ghadbane H, Suckling RJ, Page K, Crean RM, Vacchini A, De Gregorio C, Schaefer V, Constantin D, Gligoris T, Lloyd A, Hock M, Srikannathasan V, Robinson RA, Besra GS, van der Kamp MW, Mori L, Calogero R, Cole DK, De Libero G, Lepore M. Chancellor A, et al. Among authors: besra gs. J Exp Med. 2023 Sep 4;220(9):e20221939. doi: 10.1084/jem.20221939. Epub 2023 Jun 29. J Exp Med. 2023. PMID: 37382893 Free PMC article.
A structural basis for selection and cross-species reactivity of the semi-invariant NKT cell receptor in CD1d/glycolipid recognition.
Kjer-Nielsen L, Borg NA, Pellicci DG, Beddoe T, Kostenko L, Clements CS, Williamson NA, Smyth MJ, Besra GS, Reid HH, Bharadwaj M, Godfrey DI, Rossjohn J, McCluskey J. Kjer-Nielsen L, et al. Among authors: besra gs. J Exp Med. 2006 Mar 20;203(3):661-73. doi: 10.1084/jem.20051777. Epub 2006 Feb 27. J Exp Med. 2006. PMID: 16505140 Free PMC article.
Design, synthesis, and functional activity of labeled CD1d glycolipid agonists.
Jervis PJ, Polzella P, Wojno J, Jukes JP, Ghadbane H, Garcia Diaz YR, Besra GS, Cerundolo V, Cox LR. Jervis PJ, et al. Among authors: besra gs. Bioconjug Chem. 2013 Apr 17;24(4):586-94. doi: 10.1021/bc300556e. Epub 2013 Mar 19. Bioconjug Chem. 2013. PMID: 23458425 Free PMC article.
The molecular bases of δ/αβ T cell-mediated antigen recognition.
Pellicci DG, Uldrich AP, Le Nours J, Ross F, Chabrol E, Eckle SB, de Boer R, Lim RT, McPherson K, Besra G, Howell AR, Moretta L, McCluskey J, Heemskerk MH, Gras S, Rossjohn J, Godfrey DI. Pellicci DG, et al. J Exp Med. 2014 Dec 15;211(13):2599-615. doi: 10.1084/jem.20141764. Epub 2014 Dec 1. J Exp Med. 2014. PMID: 25452463 Free PMC article.
Non-glycosidic compounds can stimulate both human and mouse iNKT cells.
Jukes JP, Gileadi U, Ghadbane H, Yu TF, Shepherd D, Cox LR, Besra GS, Cerundolo V. Jukes JP, et al. Among authors: besra gs. Eur J Immunol. 2016 May;46(5):1224-34. doi: 10.1002/eji.201546114. Epub 2016 Mar 1. Eur J Immunol. 2016. PMID: 26873393 Free PMC article.
482 results