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RS6077 induces mitotic arrest and selectively activates cell death in human cancer cell lines and in a lymphoma tumor in vivo.
Sebastiani J, Puxeddu M, Nalli M, Bai R, Altieri L, Rovella P, Gaudio E, Trisciuoglio D, Spriano F, Lavia P, Fionda C, Masci D, Urbani A, Bigogno C, Dondio G, Hamel E, Bertoni F, Silvestri R, La Regina G. Sebastiani J, et al. Among authors: bertoni f. Eur J Med Chem. 2023 Jan 15;246:114997. doi: 10.1016/j.ejmech.2022.114997. Epub 2022 Dec 5. Eur J Med Chem. 2023. PMID: 36502578
Investigation of morpholine isosters for the development of a potent, selective and metabolically stable mTOR kinase inhibitor.
De Pascale M, Bissegger L, Tarantelli C, Beaufils F, Prescimone A, Mohamed Seid Hedad H, Kayali O, Orbegozo C, Raguž L, Schaefer T, Hebeisen P, Bertoni F, Wymann MP, Borsari C. De Pascale M, et al. Among authors: bertoni f. Eur J Med Chem. 2023 Feb 15;248:115038. doi: 10.1016/j.ejmech.2022.115038. Epub 2022 Dec 28. Eur J Med Chem. 2023. PMID: 36634458 Free article.
Identification of pyrrolo[3',4':3,4]cyclohepta[1,2-d][1,2]oxazoles as promising new candidates for the treatment of lymphomas.
Barreca M, Spanò V, Rocca R, Bivacqua R, Gualtieri G, Raimondi MV, Gaudio E, Bortolozzi R, Manfreda L, Bai R, Montalbano A, Alcaro S, Hamel E, Bertoni F, Viola G, Barraja P. Barreca M, et al. Among authors: bertoni f. Eur J Med Chem. 2023 Jun 5;254:115372. doi: 10.1016/j.ejmech.2023.115372. Epub 2023 Apr 12. Eur J Med Chem. 2023. PMID: 37068384
New strategies to hit hematological cancers.
Barreca M, Bertoni F, Barraja P. Barreca M, et al. Among authors: bertoni f. Eur J Med Chem. 2024 Apr 15;270:116350. doi: 10.1016/j.ejmech.2024.116350. Epub 2024 Mar 20. Eur J Med Chem. 2024. PMID: 38582688 No abstract available.
Identification of a new subclass of ALK-negative ALCL expressing aberrant levels of ERBB4 transcripts.
Scarfò I, Pellegrino E, Mereu E, Kwee I, Agnelli L, Bergaggio E, Garaffo G, Vitale N, Caputo M, Machiorlatti R, Circosta P, Abate F, Barreca A, Novero D, Mathew S, Rinaldi A, Tiacci E, Serra S, Deaglio S, Neri A, Falini B, Rabadan R, Bertoni F, Inghirami G, Piva R; European T-Cell Lymphoma Study Group. Scarfò I, et al. Among authors: bertoni f. Blood. 2016 Jan 14;127(2):221-32. doi: 10.1182/blood-2014-12-614503. Epub 2015 Oct 13. Blood. 2016. PMID: 26463425 Free article.
A DNA biosensors-based microfluidic platform for attomolar real-time detection of unamplified SARS-CoV-2 virus.
Robin P, Barnabei L, Marocco S, Pagnoncelli J, Nicolis D, Tarantelli C, Tavilla AC, Robortella R, Cascione L, Mayoraz L, Journot CMA, Mensi M, Bertoni F, Stefanini I, Gerber-Lemaire S. Robin P, et al. Among authors: bertoni f. Biosens Bioelectron X. 2023 May;13:100302. doi: 10.1016/j.biosx.2022.100302. Epub 2022 Dec 27. Biosens Bioelectron X. 2023. PMID: 36589921 Free PMC article.
Targeting CD19-positive lymphomas with the antibody-drug conjugate loncastuximab tesirine: preclinical evidence as single agent and in combination therapy.
Tarantelli C, Wald D, Munz N, Spriano F, Bruscaggin A, Cannas E, Cascione L, Gaudio E, Arribas AJ, Manjappa S, Golino G, Scalise L, Cacciapuoti MT, Zucca E, Stathis A, Inghirami G, Van Berkel PH, Rossi D, Caimi PF, Zammarchi F, Bertoni F. Tarantelli C, et al. Among authors: bertoni f. Haematologica. 2024 May 9. doi: 10.3324/haematol.2023.284197. Online ahead of print. Haematologica. 2024. PMID: 38721745 Free article.
IELSG38: phase II trial of front-line chlorambucil plus subcutaneous rituximab induction and maintenance in mucosa-associated lymphoid tissue lymphoma.
Stathis A, Pirosa MC, Orsucci L, Feugier P, Tani M, Ghesquières H, Musuraca G, Rossi FG, Merli F, Guièze R, Gyan E, Gini G, Marino D, Gressin R, Morschhauser F, Cavallo F, Palombi F, Conconi A, Tessoulin B, Tilly H, Zanni M, Cabras MG, Capochiani E, Califano C, Celli M, Pulsoni A, Angrilli F, Occhini U, Casasnovas RO, Cartron G, Devizzi L, Haioun C, Liberati AM, Houot R, Merli M, Pietrantuono G, Re F, Spina M, Landi F, Cavalli F, Bertoni F, Rossi D, Ielmini N, Borgo E, Luminari S, Zucca E, Thieblemont C. Stathis A, et al. Among authors: bertoni f. Haematologica. 2024 Feb 22. doi: 10.3324/haematol.2023.283918. Online ahead of print. Haematologica. 2024. PMID: 38385243 Free article.
ADCT-602, a Novel PBD Dimer-containing Antibody-Drug Conjugate for Treating CD22-positive Hematologic Malignancies.
Zammarchi F, Havenith KE, Sachini N, Janghra N, Chivers S, Idusogie E, Gaudio E, Tarantelli C, Bertelli F, Santos K, Tyrer P, Corbett S, Spriano F, Golino G, Cascione L, Bertoni F, Hartley JA, van Berkel PH. Zammarchi F, et al. Among authors: bertoni f. Mol Cancer Ther. 2024 Apr 2;23(4):520-531. doi: 10.1158/1535-7163.MCT-23-0506. Mol Cancer Ther. 2024. PMID: 38324336 Free PMC article.
791 results