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Drugs from nature targeting inflammation (DNTI): a successful Austrian interdisciplinary network project.
Waltenberger B, Atanasov AG, Heiss EH, Bernhard D, Rollinger JM, Breuss JM, Schuster D, Bauer R, Kopp B, Franz C, Bochkov V, Mihovilovic MD, Dirsch VM, Stuppner H. Waltenberger B, et al. Among authors: bernhard d. Monatsh Chem. 2016;147:479-491. doi: 10.1007/s00706-015-1653-y. Epub 2016 Feb 25. Monatsh Chem. 2016. PMID: 27069281 Free PMC article. Review.
Leoligin, the major lignan from Edelweiss, inhibits intimal hyperplasia of venous bypass grafts.
Reisinger U, Schwaiger S, Zeller I, Messner B, Stigler R, Wiedemann D, Mayr T, Seger C, Schachner T, Dirsch VM, Vollmar AM, Bonatti JO, Stuppner H, Laufer G, Bernhard D. Reisinger U, et al. Among authors: bernhard d. Cardiovasc Res. 2009 Jun 1;82(3):542-9. doi: 10.1093/cvr/cvp059. Epub 2009 Feb 19. Cardiovasc Res. 2009. PMID: 19228707 Free PMC article.
Leoligin, the major lignan from Edelweiss, activates cholesteryl ester transfer protein.
Duwensee K, Schwaiger S, Tancevski I, Eller K, van Eck M, Markt P, Linder T, Stanzl U, Ritsch A, Patsch JR, Schuster D, Stuppner H, Bernhard D, Eller P. Duwensee K, et al. Among authors: bernhard d. Atherosclerosis. 2011 Nov;219(1):109-15. doi: 10.1016/j.atherosclerosis.2011.07.023. Epub 2011 Jul 21. Atherosclerosis. 2011. PMID: 21820657 Free PMC article.
5-Methoxyleoligin, a lignan from Edelweiss, stimulates CYP26B1-dependent angiogenesis in vitro and induces arteriogenesis in infarcted rat hearts in vivo.
Messner B, Kern J, Wiedemann D, Schwaiger S, Türkcan A, Ploner C, Trockenbacher A, Aumayr K, Bonaros N, Laufer G, Stuppner H, Untergasser G, Bernhard D. Messner B, et al. Among authors: bernhard d. PLoS One. 2013;8(3):e58342. doi: 10.1371/journal.pone.0058342. Epub 2013 Mar 12. PLoS One. 2013. PMID: 23554885 Free PMC article.
Leoligin, the major lignan from Edelweiss, inhibits 3-hydroxy-3-methyl-glutaryl-CoA reductase and reduces cholesterol levels in ApoE-/- mice.
Scharinger B, Messner B, Türkcan A, Schuster D, Vuorinen A, Pitterl F, Heinz K, Arnhard K, Laufer G, Grimm M, Stuppner H, Oberacher H, Eller P, Ritsch A, Bernhard D. Scharinger B, et al. Among authors: bernhard d. J Mol Cell Cardiol. 2016 Oct;99:35-46. doi: 10.1016/j.yjmcc.2016.08.003. Epub 2016 Aug 3. J Mol Cell Cardiol. 2016. PMID: 27497529 Free article.
Early inhibition of endothelial retinoid uptake upon myocardial infarction restores cardiac function and prevents cell, tissue, and animal death.
Danzl K, Messner B, Doppler C, Nebert C, Abfalterer A, Sakic A, Temml V, Heinz K, Streitwieser R, Edelmann T, Mairhofer M, Grimm M, Laufer G, Zierer A, Stuppner H, Schuster D, Ploner C, Müller T, Bernhard D. Danzl K, et al. Among authors: bernhard d. J Mol Cell Cardiol. 2019 Jan;126:105-117. doi: 10.1016/j.yjmcc.2018.11.012. Epub 2018 Nov 23. J Mol Cell Cardiol. 2019. PMID: 30472251 Free article.
Tylophorine reduces protein biosynthesis and rapidly decreases cyclin D1, inhibiting vascular smooth muscle cell proliferation in vitro and in organ culture.
Joa H, Blažević T, Grojer C, Zeller I, Heiss EH, Atanasov AG, Feldler I, Gruzdaitis P, Czaloun C, Proksch P, Messner B, Bernhard D, Dirsch VM. Joa H, et al. Among authors: bernhard d. Phytomedicine. 2019 Jul;60:152938. doi: 10.1016/j.phymed.2019.152938. Epub 2019 Apr 23. Phytomedicine. 2019. PMID: 31078367
163 results