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SALL4 is a CRL3REN/KCTD11 substrate that drives Sonic Hedgehog-dependent medulloblastoma.
Lospinoso Severini L, Loricchio E, Navacci S, Basili I, Alfonsi R, Bernardi F, Moretti M, Conenna M, Cucinotta A, Coni S, Petroni M, De Smaele E, Giannini G, Maroder M, Canettieri G, Mastronuzzi A, Guardavaccaro D, Ayrault O, Infante P, Bufalieri F, Di Marcotullio L. Lospinoso Severini L, et al. Among authors: bernardi f. Cell Death Differ. 2024 Feb;31(2):170-187. doi: 10.1038/s41418-023-01246-6. Epub 2023 Dec 7. Cell Death Differ. 2024. PMID: 38062245 Free PMC article.
Itch/β-arrestin2-dependent non-proteolytic ubiquitylation of SuFu controls Hedgehog signalling and medulloblastoma tumorigenesis.
Infante P, Faedda R, Bernardi F, Bufalieri F, Lospinoso Severini L, Alfonsi R, Mazzà D, Siler M, Coni S, Po A, Petroni M, Ferretti E, Mori M, De Smaele E, Canettieri G, Capalbo C, Maroder M, Screpanti I, Kool M, Pfister SM, Guardavaccaro D, Gulino A, Di Marcotullio L. Infante P, et al. Among authors: bernardi f. Nat Commun. 2018 Mar 7;9(1):976. doi: 10.1038/s41467-018-03339-0. Nat Commun. 2018. PMID: 29515120 Free PMC article.
ERAP1 promotes Hedgehog-dependent tumorigenesis by controlling USP47-mediated degradation of βTrCP.
Bufalieri F, Infante P, Bernardi F, Caimano M, Romania P, Moretti M, Lospinoso Severini L, Talbot J, Melaiu O, Tanori M, Di Magno L, Bellavia D, Capalbo C, Puget S, De Smaele E, Canettieri G, Guardavaccaro D, Busino L, Peschiaroli A, Pazzaglia S, Giannini G, Melino G, Locatelli F, Gulino A, Ayrault O, Fruci D, Di Marcotullio L. Bufalieri F, et al. Among authors: bernardi f. Nat Commun. 2019 Jul 24;10(1):3304. doi: 10.1038/s41467-019-11093-0. Nat Commun. 2019. PMID: 31341163 Free PMC article.
Immunohistochemistry as a tool to identify ELP1-associated medulloblastoma.
Tauziède-Espariat A, Guerrini-Rousseau L, Perrier A, Torrejon J, Bernardi F, Varlet P, Hasty L, Delattre O, Beccaria K, Métais A, Ayrault O, Chrétien F, Bourdeaut F, Dufour C, Masliah-Planchon J. Tauziède-Espariat A, et al. Among authors: bernardi f. Acta Neuropathol. 2022 Apr;143(4):523-525. doi: 10.1007/s00401-022-02409-4. Epub 2022 Feb 23. Acta Neuropathol. 2022. PMID: 35199222 Free PMC article. No abstract available.
Circular RNA profiling distinguishes medulloblastoma groups and shows aberrant RMST overexpression in WNT medulloblastoma.
Rickert D, Bartl J, Picard D, Bernardi F, Qin N, Lovino M, Puget S, Meyer FD, Mahoungou Koumba I, Beez T, Varlet P, Dufour C, Fischer U, Borkhardt A, Reifenberger G, Ayrault O, Remke M. Rickert D, et al. Among authors: bernardi f. Acta Neuropathol. 2021 Jun;141(6):975-978. doi: 10.1007/s00401-021-02306-2. Epub 2021 Apr 17. Acta Neuropathol. 2021. PMID: 33866410 Free PMC article. No abstract available.
The HHIP-AS1 lncRNA promotes tumorigenicity through stabilization of dynein complex 1 in human SHH-driven tumors.
Bartl J, Zanini M, Bernardi F, Forget A, Blümel L, Talbot J, Picard D, Qin N, Cancila G, Gao Q, Nath S, Koumba IM, Wolter M, Kuonen F, Langini M, Beez T, Munoz C, Pauck D, Marquardt V, Yu H, Souphron J, Korsch M, Mölders C, Berger D, Göbbels S, Meyer FD, Scheffler B, Rotblat B, Diederichs S, Ramaswamy V, Suzuki H, Oro A, Stühler K, Stefanski A, Fischer U, Leprivier G, Willbold D, Steger G, Buell A, Kool M, Lichter P, Pfister SM, Northcott PA, Taylor MD, Borkhardt A, Reifenberger G, Ayrault O, Remke M. Bartl J, et al. Among authors: bernardi f. Nat Commun. 2022 Jul 13;13(1):4061. doi: 10.1038/s41467-022-31574-z. Nat Commun. 2022. PMID: 35831316 Free PMC article.
804 results