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Proximity-Induced Nucleic Acid Degrader (PINAD) Approach to Targeted RNA Degradation Using Small Molecules.
Mikutis S, Rebelo M, Yankova E, Gu M, Tang C, Coelho AR, Yang M, Hazemi ME, Pires de Miranda M, Eleftheriou M, Robertson M, Vassiliou GS, Adams DJ, Simas JP, Corzana F, Schneekloth JS Jr, Tzelepis K, Bernardes GJL. Mikutis S, et al. Among authors: bernardes gjl. ACS Cent Sci. 2023 Apr 26;9(5):892-904. doi: 10.1021/acscentsci.3c00015. eCollection 2023 May 24. ACS Cent Sci. 2023. PMID: 37252343 Free PMC article.
Unveiling (-)-Englerin A as a Modulator of L-Type Calcium Channels.
Rodrigues T, Sieglitz F, Somovilla VJ, Cal PM, Galione A, Corzana F, Bernardes GJ. Rodrigues T, et al. Angew Chem Int Ed Engl. 2016 Sep 5;55(37):11077-81. doi: 10.1002/anie.201604336. Epub 2016 Jul 8. Angew Chem Int Ed Engl. 2016. PMID: 27391219 Free PMC article.
Tn Antigen Mimics Based on sp(2)-Iminosugars with Affinity for an anti-MUC1 Antibody.
Fernández EM, Navo CD, Martínez-Sáez N, Gonçalves-Pereira R, Somovilla VJ, Avenoza A, Busto JH, Bernardes GJ, Jiménez-Osés G, Corzana F, Fernández JM, Mellet CO, Peregrina JM. Fernández EM, et al. Org Lett. 2016 Aug 5;18(15):3890-3. doi: 10.1021/acs.orglett.6b01899. Epub 2016 Jul 25. Org Lett. 2016. PMID: 27453399
Site-Selective Modification of Proteins with Oxetanes.
Boutureira O, Martínez-Sáez N, Brindle KM, Neves AA, Corzana F, Bernardes GJL. Boutureira O, et al. Among authors: bernardes gjl. Chemistry. 2017 May 11;23(27):6483-6489. doi: 10.1002/chem.201700745. Epub 2017 Mar 29. Chemistry. 2017. PMID: 28261889 Free PMC article.
Oxetane Grafts Installed Site-Selectively on Native Disulfides to Enhance Protein Stability and Activity In Vivo.
Martínez-Sáez N, Sun S, Oldrini D, Sormanni P, Boutureira O, Carboni F, Compañón I, Deery MJ, Vendruscolo M, Corzana F, Adamo R, Bernardes GJL. Martínez-Sáez N, et al. Among authors: bernardes gjl. Angew Chem Int Ed Engl. 2017 Nov 20;56(47):14963-14967. doi: 10.1002/anie.201708847. Epub 2017 Oct 20. Angew Chem Int Ed Engl. 2017. PMID: 28968001 Free PMC article.
Enhanced Permeability and Binding Activity of Isobutylene-Grafted Peptides.
Sun S, Compañón I, Martínez-Sáez N, Seixas JD, Boutureira O, Corzana F, Bernardes GJL. Sun S, et al. Among authors: bernardes gjl. Chembiochem. 2018 Jan 4;19(1):48-52. doi: 10.1002/cbic.201700586. Epub 2017 Nov 22. Chembiochem. 2018. PMID: 29105291 Free PMC article.
The Use of Fluoroproline in MUC1 Antigen Enables Efficient Detection of Antibodies in Patients with Prostate Cancer.
Somovilla VJ, Bermejo IA, Albuquerque IS, Martínez-Sáez N, Castro-López J, García-Martín F, Compañón I, Hinou H, Nishimura SI, Jiménez-Barbero J, Asensio JL, Avenoza A, Busto JH, Hurtado-Guerrero R, Peregrina JM, Bernardes GJL, Corzana F. Somovilla VJ, et al. Among authors: bernardes gjl. J Am Chem Soc. 2017 Dec 20;139(50):18255-18261. doi: 10.1021/jacs.7b09447. Epub 2017 Dec 12. J Am Chem Soc. 2017. PMID: 29166012 Free article.
175 results