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Combined HAT/EZH2 modulation leads to cancer-selective cell death.
Petraglia F, Singh AA, Carafa V, Nebbioso A, Conte M, Scisciola L, Valente S, Baldi A, Mandoli A, Petrizzi VB, Ingenito C, De Falco S, Cicatiello V, Apicella I, Janssen-Megens EM, Kim B, Yi G, Logie C, Heath S, Ruvo M, Wierenga ATJ, Flicek P, Yaspo ML, Della Valle V, Bernard O, Tomassi S, Novellino E, Feoli A, Sbardella G, Gut I, Vellenga E, Stunnenberg HG, Mai A, Martens JHA, Altucci L. Petraglia F, et al. Among authors: bernard o. Oncotarget. 2018 May 22;9(39):25630-25646. doi: 10.18632/oncotarget.25428. eCollection 2018 May 22. Oncotarget. 2018. PMID: 29876013 Free PMC article.
Multi-omics profiling reveals a distinctive epigenome signature for high-risk acute promyelocytic leukemia.
Singh AA, Petraglia F, Nebbioso A, Yi G, Conte M, Valente S, Mandoli A, Scisciola L, Lindeboom R, Kerstens H, Janssen-Megens EM, Pourfarzad F, Habibi E, Berentsen K, Kim B, Logie C, Heath S, Wierenga ATJ, Clarke L, Flicek P, Jansen JH, Kuijpers T, Yaspo ML, Valle VD, Bernard O, Gut I, Vellenga E, Stunnenberg HG, Mai A, Altucci L, Martens JHA. Singh AA, et al. Among authors: bernard o. Oncotarget. 2018 May 22;9(39):25647-25660. doi: 10.18632/oncotarget.25429. eCollection 2018 May 22. Oncotarget. 2018. PMID: 29876014 Free PMC article.
B-cell tumor development in Tet2-deficient mice.
Mouly E, Ghamlouch H, Della-Valle V, Scourzic L, Quivoron C, Roos-Weil D, Pawlikowska P, Saada V, Diop MK, Lopez CK, Fontenay M, Dessen P, Touw IP, Mercher T, Aoufouchi S, Bernard OA. Mouly E, et al. Blood Adv. 2018 Mar 27;2(6):703-714. doi: 10.1182/bloodadvances.2017014118. Blood Adv. 2018. PMID: 29581109 Free PMC article.
TET2-mediated 5-hydroxymethylcytosine induces genetic instability and mutagenesis.
Mahfoudhi E, Talhaoui I, Cabagnols X, Della Valle V, Secardin L, Rameau P, Bernard OA, Ishchenko AA, Abbes S, Vainchenker W, Saparbaev M, Plo I. Mahfoudhi E, et al. DNA Repair (Amst). 2016 Jul;43:78-88. doi: 10.1016/j.dnarep.2016.05.031. Epub 2016 May 24. DNA Repair (Amst). 2016. PMID: 27289557
750 results