Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation

Search Page

Filters

My NCBI Filters

Text availability

Article attribute

Article type

Publication date

Search Results

33 results

Filters applied: . Clear all
Results are displayed in a computed author sort order. The Results By Year timeline is not available.
Page 1
Induction of Aryl Hydrocarbon Receptor-Mediated Cancer Cell-Selective Apoptosis in Triple-Negative Breast Cancer Cells by a High-Affinity Benzimidazoisoquinoline.
Elson DJ, Nguyen BD, Bernales S, Chakravarty S, Jang HS, Korjeff NA, Zhang Y, Wilferd SF, Castro DJ, Plaisier CL, Finlay D, Oshima RG, Kolluri SK. Elson DJ, et al. Among authors: bernales s. ACS Pharmacol Transl Sci. 2023 Jun 7;6(7):1028-1042. doi: 10.1021/acsptsci.2c00253. eCollection 2023 Jul 14. ACS Pharmacol Transl Sci. 2023. PMID: 37470014
Dual Inhibition of Bruton's Tyrosine Kinase and Phosphoinositide-3-Kinase p110δ as a Therapeutic Approach to Treat Non-Hodgkin's B Cell Malignancies.
Alfaro J, Pérez de Arce F, Belmar S, Fuentealba G, Avila P, Ureta G, Flores C, Acuña C, Delgado L, Gaete D, Pujala B, Barde A, Nayak AK, Upendra TVR, Patel D, Chauhan S, Sharma VK, Kanno S, Almirez RG, Hung DT, Chakravarty S, Rai R, Bernales S, Quinn KP, Pham SM, McCullagh E. Alfaro J, et al. Among authors: bernales s. J Pharmacol Exp Ther. 2017 May;361(2):312-321. doi: 10.1124/jpet.116.238022. Epub 2017 Mar 15. J Pharmacol Exp Ther. 2017. PMID: 28298527
Discovery of Pyrazolopyrimidine Derivatives as Novel Dual Inhibitors of BTK and PI3Kδ.
Pujala B, Agarwal AK, Middya S, Banerjee M, Surya A, Nayak AK, Gupta A, Khare S, Guguloth R, Randive NA, Shinde BU, Thakur A, Patel DI, Raja M, Green MJ, Alfaro J, Avila P, Pérez de Arce F, Almirez RG, Kanno S, Bernales S, Hung DT, Chakravarty S, McCullagh E, Quinn KP, Rai R, Pham SM. Pujala B, et al. Among authors: bernales s. ACS Med Chem Lett. 2016 Oct 28;7(12):1161-1166. doi: 10.1021/acsmedchemlett.6b00356. eCollection 2016 Dec 8. ACS Med Chem Lett. 2016. PMID: 27994757 Free PMC article.
Design, synthesis and optimization of bis-amide derivatives as CSF1R inhibitors.
Ramachandran SA, Jadhavar PS, Miglani SK, Singh MP, Kalane DP, Agarwal AK, Sathe BD, Mukherjee K, Gupta A, Haldar S, Raja M, Singh S, Pham SM, Chakravarty S, Quinn K, Belmar S, Alfaro IE, Higgs C, Bernales S, Herrera FJ, Rai R. Ramachandran SA, et al. Among authors: bernales s. Bioorg Med Chem Lett. 2017 May 15;27(10):2153-2160. doi: 10.1016/j.bmcl.2017.03.064. Epub 2017 Mar 24. Bioorg Med Chem Lett. 2017. PMID: 28377059
Discovery of MDV6058 (PF-06952229), a selective and potent TGFβR1 inhibitor: Design, synthesis and optimization.
Pujala B, Ramachandran SA, Sonawane M, Kamble MM, Panpatil D, Adhikari S, Soni S, Subbareddy V, Shinde BU, Nayak AK, Bansal C, Gupta A, Mukherjee K, Agarwal AK, Guerrero J, Herrera FJ, Bernales S, Guha M, Chakravarty S, Pham SM, Rai R. Pujala B, et al. Among authors: bernales s. Bioorg Med Chem Lett. 2022 Nov 1;75:128979. doi: 10.1016/j.bmcl.2022.128979. Epub 2022 Sep 8. Bioorg Med Chem Lett. 2022. PMID: 36089110
Targeting prostate cancer with compounds possessing dual activity as androgen receptor antagonists and HDAC6 inhibitors.
Jadhavar PS, Ramachandran SA, Riquelme E, Gupta A, Quinn KP, Shivakumar D, Ray S, Zende D, Nayak AK, Miglani SK, Sathe BD, Raja M, Farias O, Alfaro I, Belmar S, Guerrero J, Bernales S, Chakravarty S, Hung DT, Lindquist JN, Rai R. Jadhavar PS, et al. Among authors: bernales s. Bioorg Med Chem Lett. 2016 Nov 1;26(21):5222-5228. doi: 10.1016/j.bmcl.2016.09.058. Epub 2016 Oct 4. Bioorg Med Chem Lett. 2016. PMID: 27717544
Temozolomide analogs with improved brain/plasma ratios - Exploring the possibility of enhancing the therapeutic index of temozolomide.
Rai R, Banerjee M, Wong DH, McCullagh E, Gupta A, Tripathi S, Riquelme E, Jangir R, Yadav S, Raja M, Melkani P, Dixit V, Patil U, Shrivastava R, Middya S, Olivares F, Guerrero J, Surya A, Pham SM, Bernales S, Protter AA, Hung DT, Chakravarty S. Rai R, et al. Among authors: bernales s. Bioorg Med Chem Lett. 2016 Oct 15;26(20):5103-5109. doi: 10.1016/j.bmcl.2016.08.064. Epub 2016 Aug 21. Bioorg Med Chem Lett. 2016. PMID: 27614414
Novel 3-methylindoline inhibitors of EZH2: Design, synthesis and SAR.
Ansari A, Satalkar S, Patil V, Shete AS, Kaur S, Gupta A, Singh S, Raja M, Severance DL, Bernales S, Chakravarty S, Hung DT, Pham SM, Herrera FJ, Rai R. Ansari A, et al. Among authors: bernales s. Bioorg Med Chem Lett. 2017 Jan 15;27(2):217-222. doi: 10.1016/j.bmcl.2016.11.080. Epub 2016 Nov 25. Bioorg Med Chem Lett. 2017. PMID: 27923618
Modulation of T-cell mediated immunity by dopamine receptor d5.
Prado C, Bernales S, Pacheco R. Prado C, et al. Among authors: bernales s. Endocr Metab Immune Disord Drug Targets. 2013 Jun;13(2):184-94. doi: 10.2174/1871530311313020007. Endocr Metab Immune Disord Drug Targets. 2013. PMID: 23701196 Review.
33 results