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Structural cells are key regulators of organ-specific immune responses.
Krausgruber T, Fortelny N, Fife-Gernedl V, Senekowitsch M, Schuster LC, Lercher A, Nemc A, Schmidl C, Rendeiro AF, Bergthaler A, Bock C. Krausgruber T, et al. Among authors: bergthaler a. Nature. 2020 Jul;583(7815):296-302. doi: 10.1038/s41586-020-2424-4. Epub 2020 Jul 1. Nature. 2020. PMID: 32612232 Free PMC article.
The methyltransferase Setdb2 mediates virus-induced susceptibility to bacterial superinfection.
Schliehe C, Flynn EK, Vilagos B, Richson U, Swaminanthan S, Bosnjak B, Bauer L, Kandasamy RK, Griesshammer IM, Kosack L, Schmitz F, Litvak V, Sissons J, Lercher A, Bhattacharya A, Khamina K, Trivett AL, Tessarollo L, Mesteri I, Hladik A, Merkler D, Kubicek S, Knapp S, Epstein MM, Symer DE, Aderem A, Bergthaler A. Schliehe C, et al. Among authors: bergthaler a. Nat Immunol. 2015 Jan;16(1):67-74. doi: 10.1038/ni.3046. Epub 2014 Nov 24. Nat Immunol. 2015. PMID: 25419628 Free PMC article.
MiR-155-regulated molecular network orchestrates cell fate in the innate and adaptive immune response to Mycobacterium tuberculosis.
Rothchild AC, Sissons JR, Shafiani S, Plaisier C, Min D, Mai D, Gilchrist M, Peschon J, Larson RP, Bergthaler A, Baliga NS, Urdahl KB, Aderem A. Rothchild AC, et al. Among authors: bergthaler a. Proc Natl Acad Sci U S A. 2016 Oct 11;113(41):E6172-E6181. doi: 10.1073/pnas.1608255113. Epub 2016 Sep 28. Proc Natl Acad Sci U S A. 2016. PMID: 27681624 Free PMC article.
The immune system as a social network.
Bergthaler A, Menche J. Bergthaler A, et al. Nat Immunol. 2017 Apr 18;18(5):481-482. doi: 10.1038/ni.3727. Nat Immunol. 2017. PMID: 28418389 No abstract available.
The lipid-sensor TREM2 aggravates disease in a model of LCMV-induced hepatitis.
Kosack L, Gawish R, Lercher A, Vilagos B, Hladik A, Lakovits K, Bhattacharya A, Schliehe C, Mesteri I, Knapp S, Bergthaler A. Kosack L, et al. Among authors: bergthaler a. Sci Rep. 2017 Sep 12;7(1):11289. doi: 10.1038/s41598-017-10637-y. Sci Rep. 2017. PMID: 28900132 Free PMC article.
Characterization of host proteins interacting with the lymphocytic choriomeningitis virus L protein.
Khamina K, Lercher A, Caldera M, Schliehe C, Vilagos B, Sahin M, Kosack L, Bhattacharya A, Májek P, Stukalov A, Sacco R, James LC, Pinschewer DD, Bennett KL, Menche J, Bergthaler A. Khamina K, et al. Among authors: bergthaler a. PLoS Pathog. 2017 Dec 20;13(12):e1006758. doi: 10.1371/journal.ppat.1006758. eCollection 2017 Dec. PLoS Pathog. 2017. PMID: 29261807 Free PMC article.
Human tripartite motif protein 52 is required for cell context-dependent proliferation.
Benke S, Agerer B, Haas L, Stöger M, Lercher A, Gabler L, Kiss I, Scinicariello S, Berger W, Bergthaler A, Obenauf AC, Versteeg GA. Benke S, et al. Among authors: bergthaler a. Oncotarget. 2018 Feb 5;9(17):13565-13581. doi: 10.18632/oncotarget.24422. eCollection 2018 Mar 2. Oncotarget. 2018. PMID: 29568378 Free PMC article.
The ERBB-STAT3 Axis Drives Tasmanian Devil Facial Tumor Disease.
Kosack L, Wingelhofer B, Popa A, Orlova A, Agerer B, Vilagos B, Majek P, Parapatics K, Lercher A, Ringler A, Klughammer J, Smyth M, Khamina K, Baazim H, de Araujo ED, Rosa DA, Park J, Tin G, Ahmar S, Gunning PT, Bock C, Siddle HV, Woods GM, Kubicek S, Murchison EP, Bennett KL, Moriggl R, Bergthaler A. Kosack L, et al. Among authors: bergthaler a. Cancer Cell. 2019 Jan 14;35(1):125-139.e9. doi: 10.1016/j.ccell.2018.11.018. Cancer Cell. 2019. PMID: 30645971 Free PMC article.
CD8+ T cells induce cachexia during chronic viral infection.
Baazim H, Schweiger M, Moschinger M, Xu H, Scherer T, Popa A, Gallage S, Ali A, Khamina K, Kosack L, Vilagos B, Smyth M, Lercher A, Friske J, Merkler D, Aderem A, Helbich TH, Heikenwälder M, Lang PA, Zechner R, Bergthaler A. Baazim H, et al. Among authors: bergthaler a. Nat Immunol. 2019 Jun;20(6):701-710. doi: 10.1038/s41590-019-0397-y. Epub 2019 May 20. Nat Immunol. 2019. PMID: 31110314 Free PMC article.
Type I Interferon Signaling Disrupts the Hepatic Urea Cycle and Alters Systemic Metabolism to Suppress T Cell Function.
Lercher A, Bhattacharya A, Popa AM, Caldera M, Schlapansky MF, Baazim H, Agerer B, Gürtl B, Kosack L, Májek P, Brunner JS, Vitko D, Pinter T, Genger JW, Orlova A, Pikor N, Reil D, Ozsvár-Kozma M, Kalinke U, Ludewig B, Moriggl R, Bennett KL, Menche J, Cheng PN, Schabbauer G, Trauner M, Klavins K, Bergthaler A. Lercher A, et al. Among authors: bergthaler a. Immunity. 2019 Dec 17;51(6):1074-1087.e9. doi: 10.1016/j.immuni.2019.10.014. Epub 2019 Nov 26. Immunity. 2019. PMID: 31784108 Free PMC article.
92 results