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Control of antiviral innate immune response by protein geranylgeranylation.
Yang S, Harding AT, Sweeney C, Miao D, Swan G, Zhou C, Jiang Z, Fitzgerald KA, Hammer G, Bergo MO, Kroh HK, Lacy DB, Sun C, Glogauer M, Que LG, Heaton NS, Wang D. Yang S, et al. Among authors: bergo mo. Sci Adv. 2019 May 29;5(5):eaav7999. doi: 10.1126/sciadv.aav7999. eCollection 2019 May. Sci Adv. 2019. PMID: 31149635 Free PMC article.
Control of the innate immune response by the mevalonate pathway.
Akula MK, Shi M, Jiang Z, Foster CE, Miao D, Li AS, Zhang X, Gavin RM, Forde SD, Germain G, Carpenter S, Rosadini CV, Gritsman K, Chae JJ, Hampton R, Silverman N, Gravallese EM, Kagan JC, Fitzgerald KA, Kastner DL, Golenbock DT, Bergo MO, Wang D. Akula MK, et al. Among authors: bergo mo. Nat Immunol. 2016 Aug;17(8):922-9. doi: 10.1038/ni.3487. Epub 2016 Jun 6. Nat Immunol. 2016. PMID: 27270400 Free PMC article.
Protein prenylation restrains innate immunity by inhibiting Rac1 effector interactions.
Akula MK, Ibrahim MX, Ivarsson EG, Khan OM, Kumar IT, Erlandsson M, Karlsson C, Xu X, Brisslert M, Brakebusch C, Wang D, Bokarewa M, Sayin VI, Bergo MO. Akula MK, et al. Among authors: bergo mo. Nat Commun. 2019 Sep 4;10(1):3975. doi: 10.1038/s41467-019-11606-x. Nat Commun. 2019. PMID: 31484924 Free PMC article.
Lack of RAC1 in macrophages protects against atherosclerosis.
Bandaru S, Ala C, Ekstrand M, Akula MK, Pedrelli M, Liu X, Bergström G, Håversen L, Borén J, Bergo MO, Akyürek LM. Bandaru S, et al. Among authors: bergo mo. PLoS One. 2020 Sep 17;15(9):e0239284. doi: 10.1371/journal.pone.0239284. eCollection 2020. PLoS One. 2020. PMID: 32941503 Free PMC article.
Targeting Zfp148 activates p53 and reduces tumor initiation in the gut.
Nilton A, Sayin VI, Zou ZV, Sayin SI, Bondjers C, Gul N, Agren P, Fogelstrand P, Nilsson O, Bergo MO, Lindahl P. Nilton A, et al. Among authors: bergo mo. Oncotarget. 2016 Aug 30;7(35):56183-56192. doi: 10.18632/oncotarget.10899. Oncotarget. 2016. PMID: 27487143 Free PMC article.
Targeting Filamin A Reduces Macrophage Activity and Atherosclerosis.
Bandaru S, Ala C, Salimi R, Akula MK, Ekstrand M, Devarakonda S, Karlsson J, Van den Eynden J, Bergström G, Larsson E, Levin M, Borén J, Bergo MO, Akyürek LM. Bandaru S, et al. Among authors: bergo mo. Circulation. 2019 Jul 2;140(1):67-79. doi: 10.1161/CIRCULATIONAHA.119.039697. Epub 2019 Apr 24. Circulation. 2019. PMID: 31014088
111 results