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Disease-associated inosine misincorporation into RNA hinders translation.
Schroader JH, Jones LA, Meng R, Shorrock HK, Richardson JI, Shaughnessy SM, Lin Q, Begley TJ, Berglund JA, Fuchs G, Handley MT, Reddy K. Schroader JH, et al. Among authors: berglund ja. Nucleic Acids Res. 2022 Sep 9;50(16):9306-9318. doi: 10.1093/nar/gkac709. Nucleic Acids Res. 2022. PMID: 35979951 Free PMC article.
An engineered RNA binding protein with improved splicing regulation.
Hale MA, Richardson JI, Day RC, McConnell OL, Arboleda J, Wang ET, Berglund JA. Hale MA, et al. Among authors: berglund ja. Nucleic Acids Res. 2018 Apr 6;46(6):3152-3168. doi: 10.1093/nar/gkx1304. Nucleic Acids Res. 2018. PMID: 29309648 Free PMC article.
A CTG repeat-selective chemical screen identifies microtubule inhibitors as selective modulators of toxic CUG RNA levels.
Reddy K, Jenquin JR, McConnell OL, Cleary JD, Richardson JI, Pinto BS, Haerle MC, Delgado E, Planco L, Nakamori M, Wang ET, Berglund JA. Reddy K, et al. Among authors: berglund ja. Proc Natl Acad Sci U S A. 2019 Oct 15;116(42):20991-21000. doi: 10.1073/pnas.1901893116. Epub 2019 Sep 30. Proc Natl Acad Sci U S A. 2019. PMID: 31570586 Free PMC article.
Drug Screen Tugs at Common Thread for Repeat Disorders.
Reddy K, Cleary JD, Berglund JA. Reddy K, et al. Among authors: berglund ja. Trends Pharmacol Sci. 2020 Feb;41(2):71-73. doi: 10.1016/j.tips.2019.12.004. Epub 2020 Jan 8. Trends Pharmacol Sci. 2020. PMID: 31926601
[No title available]
[No authors listed] [No authors listed] PMID: 33973007
CCG•CGG interruptions in high-penetrance SCA8 families increase RAN translation and protein toxicity.
Perez BA, Shorrock HK, Banez-Coronel M, Zu T, Romano LE, Laboissonniere LA, Reid T, Ikeda Y, Reddy K, Gomez CM, Bird T, Ashizawa T, Schut LJ, Brusco A, Berglund JA, Hasholt LF, Nielsen JE, Subramony SH, Ranum LP. Perez BA, et al. Among authors: berglund ja. EMBO Mol Med. 2021 Nov 8;13(11):e14095. doi: 10.15252/emmm.202114095. Epub 2021 Oct 11. EMBO Mol Med. 2021. PMID: 34632710 Free PMC article.
80 results