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Stamp2 Protects From Maladaptive Structural Remodeling and Systolic Dysfunction in Post-Ischemic Hearts by Attenuating Neutrophil Activation.
Mollenhauer M, Bokredenghel S, Geißen S, Klinke A, Morstadt T, Torun M, Strauch S, Schumacher W, Maass M, Konradi J, Peters VBM, Berghausen E, Vantler M, Rosenkranz S, Mehrkens D, Braumann S, Nettersheim F, Hof A, Simsekyilmaz S, Winkels H, Rudolph V, Baldus S, Adam M, Freyhaus HT. Mollenhauer M, et al. Among authors: berghausen e. Front Immunol. 2021 Oct 6;12:701721. doi: 10.3389/fimmu.2021.701721. eCollection 2021. Front Immunol. 2021. PMID: 34691017 Free PMC article.
Myeloperoxidase aggravates pulmonary arterial hypertension by activation of vascular Rho-kinase.
Klinke A, Berghausen E, Friedrichs K, Molz S, Lau D, Remane L, Berlin M, Kaltwasser C, Adam M, Mehrkens D, Mollenhauer M, Manchanda K, Ravekes T, Heresi GA, Aytekin M, Dweik RA, Hennigs JK, Kubala L, Michaëlsson E, Rosenkranz S, Rudolph TK, Hazen SL, Klose H, Schermuly RT, Rudolph V, Baldus S. Klinke A, et al. Among authors: berghausen e. JCI Insight. 2018 Jun 7;3(11):e97530. doi: 10.1172/jci.insight.97530. eCollection 2018 Jun 7. JCI Insight. 2018. PMID: 29875311 Free PMC article.
Genetic Ablation of PDGF-Dependent Signaling Pathways Abolishes Vascular Remodeling and Experimental Pulmonary Hypertension.
Ten Freyhaus H, Berghausen EM, Janssen W, Leuchs M, Zierden M, Murmann K, Klinke A, Vantler M, Caglayan E, Kramer T, Baldus S, Schermuly RT, Tallquist MD, Rosenkranz S. Ten Freyhaus H, et al. Among authors: berghausen em. Arterioscler Thromb Vasc Biol. 2015 May;35(5):1236-45. doi: 10.1161/ATVBAHA.114.304864. Epub 2015 Mar 5. Arterioscler Thromb Vasc Biol. 2015. PMID: 25745058 Free PMC article.
Disrupted PI3K subunit p110α signaling protects against pulmonary hypertension and reverses established disease in rodents.
Berghausen EM, Janssen W, Vantler M, Gnatzy-Feik LL, Krause M, Behringer A, Joseph C, Zierden M, Freyhaus HT, Klinke A, Baldus S, Alcazar MA, Savai R, Pullamsetti SS, Wong DW, Boor P, Zhao JJ, Schermuly RT, Rosenkranz S. Berghausen EM, et al. J Clin Invest. 2021 Oct 1;131(19):e136939. doi: 10.1172/JCI136939. J Clin Invest. 2021. PMID: 34596056 Free PMC article.
Class IA Phosphatidylinositol 3-Kinase Isoform p110α Mediates Vascular Remodeling.
Vantler M, Jesus J, Leppänen O, Scherner M, Berghausen EM, Mustafov L, Chen X, Kramer T, Zierden M, Gerhardt M, Ten Freyhaus H, Blaschke F, Sterner-Kock A, Baldus S, Zhao JJ, Rosenkranz S. Vantler M, et al. Arterioscler Thromb Vasc Biol. 2015 Jun;35(6):1434-44. doi: 10.1161/ATVBAHA.114.304887. Epub 2015 Apr 23. Arterioscler Thromb Vasc Biol. 2015. PMID: 25908763
Imatinib mesylate for the treatment of pulmonary arterial hypertension.
ten Freyhaus H, Dumitrescu D, Berghausen E, Vantler M, Caglayan E, Rosenkranz S. ten Freyhaus H, et al. Among authors: berghausen e. Expert Opin Investig Drugs. 2012 Jan;21(1):119-34. doi: 10.1517/13543784.2012.632408. Epub 2011 Nov 11. Expert Opin Investig Drugs. 2012. PMID: 22074410 Review.
18 results