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DDX3 regulates endoplasmic reticulum stress-induced ATF4 expression.
Adjibade P, Grenier St-Sauveur V, Bergeman J, Huot ME, Khandjian EW, Mazroui R. Adjibade P, et al. Among authors: bergeman j. Sci Rep. 2017 Oct 23;7(1):13832. doi: 10.1038/s41598-017-14262-7. Sci Rep. 2017. PMID: 29062139 Free PMC article.
The oncometabolite 2-hydroxyglutarate activates the mTOR signalling pathway.
Carbonneau M, M Gagné L, Lalonde ME, Germain MA, Motorina A, Guiot MC, Secco B, Vincent EE, Tumber A, Hulea L, Bergeman J, Oppermann U, Jones RG, Laplante M, Topisirovic I, Petrecca K, Huot MÉ, Mallette FA. Carbonneau M, et al. Among authors: bergeman j. Nat Commun. 2016 Sep 14;7:12700. doi: 10.1038/ncomms12700. Nat Commun. 2016. PMID: 27624942 Free PMC article.