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Human iPSC modelling of a familial form of atrial fibrillation reveals a gain of function of If and ICaL in patient-derived cardiomyocytes.
Benzoni P, Campostrini G, Landi S, Bertini V, Marchina E, Iascone M, Ahlberg G, Olesen MS, Crescini E, Mora C, Bisleri G, Muneretto C, Ronca R, Presta M, Poliani PL, Piovani G, Verardi R, Di Pasquale E, Consiglio A, Raya A, Torre E, Lodrini AM, Milanesi R, Rocchetti M, Baruscotti M, DiFrancesco D, Memo M, Barbuti A, Dell'Era P. Benzoni P, et al. Cardiovasc Res. 2020 May 1;116(6):1147-1160. doi: 10.1093/cvr/cvz217. Cardiovasc Res. 2020. PMID: 31504264 Free PMC article.
A detailed characterization of the hyperpolarization-activated "funny" current (If) in human-induced pluripotent stem cell (iPSC)-derived cardiomyocytes with pacemaker activity.
Giannetti F, Benzoni P, Campostrini G, Milanesi R, Bucchi A, Baruscotti M, Dell'Era P, Rossini A, Barbuti A. Giannetti F, et al. Among authors: benzoni p. Pflugers Arch. 2021 Jul;473(7):1009-1021. doi: 10.1007/s00424-021-02571-w. Epub 2021 May 2. Pflugers Arch. 2021. PMID: 33934225 Free PMC article.
Ion channel dysfunction and fibrosis in atrial fibrillation: Two sides of the same coin.
Arabia G, Bellicini MG, Cersosimo A, Memo M, Mazzarotto F, Inciardi RM, Cerini M, Chen LY, Aboelhassan M, Benzoni P, Mitacchione G, Bontempi L, Curnis A. Arabia G, et al. Among authors: benzoni p. Pacing Clin Electrophysiol. 2024 Mar;47(3):417-428. doi: 10.1111/pace.14944. Epub 2024 Feb 20. Pacing Clin Electrophysiol. 2024. PMID: 38375940 Review.
21 results