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Identification of Novel, Selective Ataxia-Telangiectasia Mutated Kinase Inhibitors with the Ability to Penetrate the Blood-Brain Barrier: The Discovery of AZD1390.
J Med Chem. 2024 Feb 22;67(4):3090-3111. doi: 10.1021/acs.jmedchem.3c02277. Epub 2024 Feb 2.
J Med Chem. 2024.
PMID: 38306388
Advances in the Specificity of Mass Spectrometry and Nuclear Magnetic Resonance Spectroscopy Based Structural Characterisation Methods for Synthetic Oligonucleotides.
Dias DM, Coombes SR, Benstead D, Whittaker DTE, Ray A, Xu J.
Dias DM, et al. Among authors: benstead d.
J Pharm Sci. 2023 Sep;112(9):2524-2531. doi: 10.1016/j.xphs.2023.04.013. Epub 2023 Apr 25.
J Pharm Sci. 2023.
PMID: 37105438
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Strategies for Identity Testing of Therapeutic Oligonucleotide Drug Substances and Drug Products.
Capaldi D, Akhtar N, Atherton T, Benstead D, Charaf A, De Vijlder T, Heatherington C, Hoernschemeyer J, Jiang H, Rieder U, Ring F, Peter R, Stolee JA, Wechselberger R.
Capaldi D, et al. Among authors: benstead d.
Nucleic Acid Ther. 2020 Oct;30(5):249-264. doi: 10.1089/nat.2020.0878. Epub 2020 Aug 26.
Nucleic Acid Ther. 2020.
PMID: 32857010
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