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Page 1
Restoring tumor immunogenicity with dendritic cell reprogramming.
Zimmermannova O, Ferreira AG, Ascic E, Velasco Santiago M, Kurochkin I, Hansen M, Met Ö, Caiado I, Shapiro IE, Michaux J, Humbert M, Soto-Cabrera D, Benonisson H, Silvério-Alves R, Gomez-Jimenez D, Bernardo C, Bauden M, Andersson R, Höglund M, Miharada K, Nakamura Y, Hugues S, Greiff L, Lindstedt M, Rosa FF, Pires CF, Bassani-Sternberg M, Svane IM, Pereira CF. Zimmermannova O, et al. Among authors: benonisson h. Sci Immunol. 2023 Jul 14;8(85):eadd4817. doi: 10.1126/sciimmunol.add4817. Epub 2023 Jul 7. Sci Immunol. 2023. PMID: 37418548 Free PMC article.
A Restricted Role for FcγR in the Regulation of Adaptive Immunity.
Fransen MF, Benonisson H, van Maren WW, Sow HS, Breukel C, Linssen MM, Claassens JWC, Brouwers C, van der Kaa J, Camps M, Kleinovink JW, Vonk KK, van Heiningen S, Klar N, van Beek L, van Harmelen V, Daxinger L, Nandakumar KS, Holmdahl R, Coward C, Lin Q, Hirose S, Salvatori D, van Hall T, van Kooten C, Mastroeni P, Ossendorp F, Verbeek JS. Fransen MF, et al. Among authors: benonisson h. J Immunol. 2018 Apr 15;200(8):2615-2626. doi: 10.4049/jimmunol.1700429. Epub 2018 Mar 9. J Immunol. 2018. PMID: 29523656 Free PMC article.
Afucosylated IgG Targets FcγRIV for Enhanced Tumor Therapy in Mice.
Braster R, Bögels M, Benonisson H, Wuhrer M, Plomp R, Bentlage AEH, Korthouwer R, Visser R, Verbeek JS, van Egmond M, Vidarsson G. Braster R, et al. Among authors: benonisson h. Cancers (Basel). 2021 May 14;13(10):2372. doi: 10.3390/cancers13102372. Cancers (Basel). 2021. PMID: 34069226 Free PMC article.
FcγR interaction is not required for effective anti-PD-L1 immunotherapy but can add additional benefit depending on the tumor model.
Sow HS, Benonisson H, Breukel C, Visser R, Verhagen OJHM, Bentlage AEH, Brouwers C, Claassens JWC, Linssen MM, Camps M, van Hall T, Ossendorp F, Fransen MF, Vidarsson G, Verbeek JS. Sow HS, et al. Among authors: benonisson h. Int J Cancer. 2019 Jan 15;144(2):345-354. doi: 10.1002/ijc.31899. Epub 2018 Nov 12. Int J Cancer. 2019. PMID: 30259976 Free article.