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Homocysteine and coronary heart disease: meta-analysis of MTHFR case-control studies, avoiding publication bias.
Clarke R, Bennett DA, Parish S, Verhoef P, Dötsch-Klerk M, Lathrop M, Xu P, Nordestgaard BG, Holm H, Hopewell JC, Saleheen D, Tanaka T, Anand SS, Chambers JC, Kleber ME, Ouwehand WH, Yamada Y, Elbers C, Peters B, Stewart AF, Reilly MM, Thorand B, Yusuf S, Engert JC, Assimes TL, Kooner J, Danesh J, Watkins H, Samani NJ, Collins R, Peto R; MTHFR Studies Collaborative Group. Clarke R, et al. Among authors: bennett da. PLoS Med. 2012 Feb;9(2):e1001177. doi: 10.1371/journal.pmed.1001177. Epub 2012 Feb 21. PLoS Med. 2012. PMID: 22363213 Free PMC article.
The exon 1-8C/G SNP in the PSMA6 gene contributes only a small amount to the burden of myocardial infarction in 6946 cases and 2720 controls from a United Kingdom population.
Bennett DA, Xu P, Clarke R, Zondervan K, Parish S, Palmer A, Cardon L, Peto R, Lathrop M, Collins R; International Study of Infarct Survival Collaborators. Bennett DA, et al. Eur J Hum Genet. 2008 Apr;16(4):480-6. doi: 10.1038/sj.ejhg.5201948. Epub 2008 Jan 30. Eur J Hum Genet. 2008. PMID: 18231128
Genetic Loci associated with C-reactive protein levels and risk of coronary heart disease.
Elliott P, Chambers JC, Zhang W, Clarke R, Hopewell JC, Peden JF, Erdmann J, Braund P, Engert JC, Bennett D, Coin L, Ashby D, Tzoulaki I, Brown IJ, Mt-Isa S, McCarthy MI, Peltonen L, Freimer NB, Farrall M, Ruokonen A, Hamsten A, Lim N, Froguel P, Waterworth DM, Vollenweider P, Waeber G, Jarvelin MR, Mooser V, Scott J, Hall AS, Schunkert H, Anand SS, Collins R, Samani NJ, Watkins H, Kooner JS. Elliott P, et al. JAMA. 2009 Jul 1;302(1):37-48. doi: 10.1001/jama.2009.954. JAMA. 2009. PMID: 19567438 Free PMC article.
Genetic variants associated with Lp(a) lipoprotein level and coronary disease.
Clarke R, Peden JF, Hopewell JC, Kyriakou T, Goel A, Heath SC, Parish S, Barlera S, Franzosi MG, Rust S, Bennett D, Silveira A, Malarstig A, Green FR, Lathrop M, Gigante B, Leander K, de Faire U, Seedorf U, Hamsten A, Collins R, Watkins H, Farrall M; PROCARDIS Consortium. Clarke R, et al. N Engl J Med. 2009 Dec 24;361(26):2518-28. doi: 10.1056/NEJMoa0902604. N Engl J Med. 2009. PMID: 20032323 Free article.
Effects of lowering homocysteine levels with B vitamins on cardiovascular disease, cancer, and cause-specific mortality: Meta-analysis of 8 randomized trials involving 37 485 individuals.
Clarke R, Halsey J, Lewington S, Lonn E, Armitage J, Manson JE, Bønaa KH, Spence JD, Nygård O, Jamison R, Gaziano JM, Guarino P, Bennett D, Mir F, Peto R, Collins R; B-Vitamin Treatment Trialists' Collaboration. Clarke R, et al. Arch Intern Med. 2010 Oct 11;170(18):1622-31. doi: 10.1001/archinternmed.2010.348. Arch Intern Med. 2010. PMID: 20937919 Review.
Effects of homocysteine lowering with B vitamins on cognitive aging: meta-analysis of 11 trials with cognitive data on 22,000 individuals.
Clarke R, Bennett D, Parish S, Lewington S, Skeaff M, Eussen SJ, Lewerin C, Stott DJ, Armitage J, Hankey GJ, Lonn E, Spence JD, Galan P, de Groot LC, Halsey J, Dangour AD, Collins R, Grodstein F; B-Vitamin Treatment Trialists’ Collaboration. Clarke R, et al. Am J Clin Nutr. 2014 Aug;100(2):657-66. doi: 10.3945/ajcn.113.076349. Epub 2014 Jun 25. Am J Clin Nutr. 2014. PMID: 24965307 Free PMC article.
1,646 results