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Purine synthesis suppression reduces the development and progression of pulmonary hypertension in rodent models.
Ma Q, Yang Q, Xu J, Sellers HG, Brown ZL, Liu Z, Bordan Z, Shi X, Zhao D, Cai Y, Pareek V, Zhang C, Wu G, Dong Z, Verin AD, Gan L, Du Q, Benkovic SJ, Xu S, Asara JM, Ben-Sahra I, Barman S, Su Y, Fulton DJR, Huo Y. Ma Q, et al. Among authors: benkovic sj. Eur Heart J. 2023 Apr 7;44(14):1265-1279. doi: 10.1093/eurheartj/ehad044. Eur Heart J. 2023. PMID: 36721994 Free PMC article.
ATIC-Associated De Novo Purine Synthesis Is Critically Involved in Proliferative Arterial Disease.
Ma Q, Yang Q, Xu J, Zhang X, Kim D, Liu Z, Da Q, Mao X, Zhou Y, Cai Y, Pareek V, Kim HW, Wu G, Dong Z, Song WL, Gan L, Zhang C, Hong M, Benkovic SJ, Weintraub NL, Fulton D Jr, Asara JM, Ben-Sahra I, Huo Y. Ma Q, et al. Among authors: benkovic sj. Circulation. 2022 Nov 8;146(19):1444-1460. doi: 10.1161/CIRCULATIONAHA.121.058901. Epub 2022 Sep 8. Circulation. 2022. PMID: 36073366 Free PMC article.
The Purinosome: A Case Study for a Mammalian Metabolon.
Pedley AM, Pareek V, Benkovic SJ. Pedley AM, et al. Among authors: benkovic sj. Annu Rev Biochem. 2022 Jun 21;91:89-106. doi: 10.1146/annurev-biochem-032620-105728. Epub 2022 Mar 23. Annu Rev Biochem. 2022. PMID: 35320684 Free PMC article. Review.
Metabolic channeling: predictions, deductions, and evidence.
Pareek V, Sha Z, He J, Wingreen NS, Benkovic SJ. Pareek V, et al. Among authors: benkovic sj. Mol Cell. 2021 Sep 16;81(18):3775-3785. doi: 10.1016/j.molcel.2021.08.030. Mol Cell. 2021. PMID: 34547238 Free PMC article. Review.
From Bioorganic Models to Cells.
Benkovic SJ. Benkovic SJ. Annu Rev Biochem. 2021 Jun 20;90:57-76. doi: 10.1146/annurev-biochem-062320-062929. Annu Rev Biochem. 2021. PMID: 34153218
508 results