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SAMHD1 phosphorylation and cytoplasmic relocalization after human cytomegalovirus infection limits its antiviral activity.
De Meo S, Dell'Oste V, Molfetta R, Tassinari V, Lotti LV, Vespa S, Pignoloni B, Covino DA, Fantuzzi L, Bona R, Zingoni A, Nardone I, Biolatti M, Coscia A, Paolini R, Benkirane M, Edfors F, Sandalova T, Achour A, Hiscott J, Landolfo S, Santoni A, Cerboni C. De Meo S, et al. Among authors: benkirane m. PLoS Pathog. 2020 Sep 28;16(9):e1008855. doi: 10.1371/journal.ppat.1008855. eCollection 2020 Sep. PLoS Pathog. 2020. PMID: 32986788 Free PMC article.
Phosphorylation of murine SAMHD1 regulates its antiretroviral activity.
Wittmann S, Behrendt R, Eissmann K, Volkmann B, Thomas D, Ebert T, Cribier A, Benkirane M, Hornung V, Bouzas NF, Gramberg T. Wittmann S, et al. Among authors: benkirane m. Retrovirology. 2015 Dec 15;12:103. doi: 10.1186/s12977-015-0229-6. Retrovirology. 2015. PMID: 26667483 Free PMC article.
How SAMHD1 changes our view of viral restriction.
Laguette N, Benkirane M. Laguette N, et al. Among authors: benkirane m. Trends Immunol. 2012 Jan;33(1):26-33. doi: 10.1016/j.it.2011.11.002. Epub 2011 Dec 15. Trends Immunol. 2012. PMID: 22177690 Free PMC article. Review.
SAMHD1 restricts HIV-1 reverse transcription in quiescent CD4(+) T-cells.
Descours B, Cribier A, Chable-Bessia C, Ayinde D, Rice G, Crow Y, Yatim A, Schwartz O, Laguette N, Benkirane M. Descours B, et al. Among authors: benkirane m. Retrovirology. 2012 Oct 23;9:87. doi: 10.1186/1742-4690-9-87. Retrovirology. 2012. PMID: 23092122 Free PMC article.
Dasatinib inhibits HIV-1 replication through the interference of SAMHD1 phosphorylation in CD4+ T cells.
Bermejo M, López-Huertas MR, García-Pérez J, Climent N, Descours B, Ambrosioni J, Mateos E, Rodríguez-Mora S, Rus-Bercial L, Benkirane M, Miró JM, Plana M, Alcamí J, Coiras M. Bermejo M, et al. Among authors: benkirane m. Biochem Pharmacol. 2016 Apr 15;106:30-45. doi: 10.1016/j.bcp.2016.02.002. Epub 2016 Feb 4. Biochem Pharmacol. 2016. PMID: 26851491
SAMHD1 restricts the replication of human immunodeficiency virus type 1 by depleting the intracellular pool of deoxynucleoside triphosphates.
Lahouassa H, Daddacha W, Hofmann H, Ayinde D, Logue EC, Dragin L, Bloch N, Maudet C, Bertrand M, Gramberg T, Pancino G, Priet S, Canard B, Laguette N, Benkirane M, Transy C, Landau NR, Kim B, Margottin-Goguet F. Lahouassa H, et al. Among authors: benkirane m. Nat Immunol. 2012 Feb 12;13(3):223-228. doi: 10.1038/ni.2236. Nat Immunol. 2012. PMID: 22327569 Free PMC article.
SAMHD1 Enhances Chikungunya and Zika Virus Replication in Human Skin Fibroblasts.
Wichit S, Hamel R, Zanzoni A, Diop F, Cribier A, Talignani L, Diack A, Ferraris P, Liegeois F, Urbach S, Ekchariyawat P, Merits A, Yssel H, Benkirane M, Missé D. Wichit S, et al. Among authors: benkirane m. Int J Mol Sci. 2019 Apr 5;20(7):1695. doi: 10.3390/ijms20071695. Int J Mol Sci. 2019. PMID: 30959732 Free PMC article.
137 results