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EPAC1 inhibition protects the heart from doxorubicin-induced toxicity.
Mazevet M, Belhadef A, Ribeiro M, Dayde D, Llach A, Laudette M, Belleville T, Mateo P, Gressette M, Lefebvre F, Chen J, Bachelot-Loza C, Rucker-Martin C, Lezoualch F, Crozatier B, Benitah JP, Vozenin MC, Fischmeister R, Gomez AM, Lemaire C, Morel E. Mazevet M, et al. Among authors: benitah jp. Elife. 2023 Aug 8;12:e83831. doi: 10.7554/eLife.83831. Elife. 2023. PMID: 37551870 Free PMC article.
The cAMP binding protein Epac modulates Ca2+ sparks by a Ca2+/calmodulin kinase signalling pathway in rat cardiac myocytes.
Pereira L, Métrich M, Fernández-Velasco M, Lucas A, Leroy J, Perrier R, Morel E, Fischmeister R, Richard S, Bénitah JP, Lezoualc'h F, Gómez AM. Pereira L, et al. Among authors: benitah jp. J Physiol. 2007 Sep 1;583(Pt 2):685-94. doi: 10.1113/jphysiol.2007.133066. Epub 2007 Jun 28. J Physiol. 2007. PMID: 17599964 Free PMC article.
Epac enhances excitation-transcription coupling in cardiac myocytes.
Pereira L, Ruiz-Hurtado G, Morel E, Laurent AC, Métrich M, Domínguez-Rodríguez A, Lauton-Santos S, Lucas A, Benitah JP, Bers DM, Lezoualc'h F, Gómez AM. Pereira L, et al. Among authors: benitah jp. J Mol Cell Cardiol. 2012 Jan;52(1):283-91. doi: 10.1016/j.yjmcc.2011.10.016. Epub 2011 Oct 29. J Mol Cell Cardiol. 2012. PMID: 22056318 Free PMC article.
Epac in cardiac calcium signaling.
Ruiz-Hurtado G, Morel E, Domínguez-Rodríguez A, Llach A, Lezoualc'h F, Benitah JP, Gomez AM. Ruiz-Hurtado G, et al. Among authors: benitah jp. J Mol Cell Cardiol. 2013 May;58:162-71. doi: 10.1016/j.yjmcc.2012.11.021. Epub 2012 Dec 7. J Mol Cell Cardiol. 2013. PMID: 23220153 Review.
Specific Activation of the Alternative Cardiac Promoter of Cacna1c by the Mineralocorticoid Receptor.
Mesquita TR, Auguste G, Falcón D, Ruiz-Hurtado G, Salazar-Enciso R, Sabourin J, Lefebvre F, Viengchareun S, Kobeissy H, Lechène P, Nicolas V, Fernandez-Celis A, Gómez S, Lauton Santos S, Morel E, Rueda A, López-Andrés N, Gómez AM, Lombès M, Benitah JP. Mesquita TR, et al. Among authors: benitah jp. Circ Res. 2018 Mar 30;122(7):e49-e61. doi: 10.1161/CIRCRESAHA.117.312451. Epub 2018 Feb 21. Circ Res. 2018. PMID: 29467196
Progression of excitation-contraction coupling defects in doxorubicin cardiotoxicity.
Llach A, Mazevet M, Mateo P, Villejouvert O, Ridoux A, Rucker-Martin C, Ribeiro M, Fischmeister R, Crozatier B, Benitah JP, Morel E, Gómez AM. Llach A, et al. Among authors: benitah jp. J Mol Cell Cardiol. 2019 Jan;126:129-139. doi: 10.1016/j.yjmcc.2018.11.019. Epub 2018 Nov 28. J Mol Cell Cardiol. 2019. PMID: 30500377
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