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Evolutionary origins of a bioactive peptide buried within Preproalbumin.
Elliott AG, Delay C, Liu H, Phua Z, Rosengren KJ, Benfield AH, Panero JL, Colgrave ML, Jayasena AS, Dunse KM, Anderson MA, Schilling EE, Ortiz-Barrientos D, Craik DJ, Mylne JS. Elliott AG, et al. Among authors: benfield ah. Plant Cell. 2014 Mar;26(3):981-95. doi: 10.1105/tpc.114.123620. Epub 2014 Mar 28. Plant Cell. 2014. PMID: 24681618 Free PMC article.
Redesigned Spider Peptide with Improved Antimicrobial and Anticancer Properties.
Troeira Henriques S, Lawrence N, Chaousis S, Ravipati AS, Cheneval O, Benfield AH, Elliott AG, Kavanagh AM, Cooper MA, Chan LY, Huang YH, Craik DJ. Troeira Henriques S, et al. Among authors: benfield ah. ACS Chem Biol. 2017 Sep 15;12(9):2324-2334. doi: 10.1021/acschembio.7b00459. Epub 2017 Aug 8. ACS Chem Biol. 2017. PMID: 28741926
Mechanisms of bacterial membrane permeabilization by crotalicidin (Ctn) and its fragment Ctn(15-34), antimicrobial peptides from rattlesnake venom.
Pérez-Peinado C, Dias SA, Domingues MM, Benfield AH, Freire JM, Rádis-Baptista G, Gaspar D, Castanho MARB, Craik DJ, Henriques ST, Veiga AS, Andreu D. Pérez-Peinado C, et al. Among authors: benfield ah. J Biol Chem. 2018 Feb 2;293(5):1536-1549. doi: 10.1074/jbc.RA117.000125. Epub 2017 Dec 18. J Biol Chem. 2018. PMID: 29255091 Free PMC article.
Cell Membrane Composition Drives Selectivity and Toxicity of Designed Cyclic Helix-Loop-Helix Peptides with Cell Penetrating and Tumor Suppressor Properties.
Philippe GJ, Gaspar D, Sheng C, Huang YH, Benfield AH, Condon ND, Weidmann J, Lawrence N, Löwer A, Castanho MARB, Craik DJ, Troeira Henriques S. Philippe GJ, et al. Among authors: benfield ah. ACS Chem Biol. 2019 Sep 20;14(9):2071-2087. doi: 10.1021/acschembio.9b00593. Epub 2019 Aug 21. ACS Chem Biol. 2019. PMID: 31390185
Cyclic gomesin, a stable redesigned spider peptide able to enter cancer cells.
Benfield AH, Defaus S, Lawrence N, Chaousis S, Condon N, Cheneval O, Huang YH, Chan LY, Andreu D, Craik DJ, Henriques ST. Benfield AH, et al. Biochim Biophys Acta Biomembr. 2021 Jan 1;1863(1):183480. doi: 10.1016/j.bbamem.2020.183480. Epub 2020 Sep 24. Biochim Biophys Acta Biomembr. 2021. PMID: 32979382 Free article.
24 results