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The CSF-1R inhibitor pexidartinib affects FLT3-dependent DC differentiation and may antagonize durvalumab effect in patients with advanced cancers.
Voissière A, Gomez-Roca C, Chabaud S, Rodriguez C, Nkodia A, Berthet J, Montane L, Bidaux AS, Treilleux I, Eberst L, Terret C, Korakis I, Garin G, Pérol D, Delord JP, Caux C, Dubois B, Ménétrier-Caux C, Bendriss-Vermare N, Cassier PA. Voissière A, et al. Among authors: bendriss vermare n. Sci Transl Med. 2024 Jan 24;16(731):eadd1834. doi: 10.1126/scitranslmed.add1834. Epub 2024 Jan 24. Sci Transl Med. 2024. PMID: 38266104
A Milestone Review on How Macrophages Affect Tumor Growth.
Caux C, Ramos RN, Prendergast GC, Bendriss-Vermare N, Ménétrier-Caux C. Caux C, et al. Cancer Res. 2016 Nov 15;76(22):6439-6442. doi: 10.1158/0008-5472.CAN-16-2631. Cancer Res. 2016. PMID: 28148676 No abstract available.
CD163+ tumor-associated macrophage accumulation in breast cancer patients reflects both local differentiation signals and systemic skewing of monocytes.
Ramos RN, Rodriguez C, Hubert M, Ardin M, Treilleux I, Ries CH, Lavergne E, Chabaud S, Colombe A, Trédan O, Guedes HG, Laginha F, Richer W, Piaggio E, Barbuto JAM, Caux C, Ménétrier-Caux C, Bendriss-Vermare N. Ramos RN, et al. Clin Transl Immunology. 2020 Feb 13;9(2):e1108. doi: 10.1002/cti2.1108. eCollection 2020. Clin Transl Immunology. 2020. PMID: 32082570 Free PMC article.
IFN-III is selectively produced by cDC1 and predicts good clinical outcome in breast cancer.
Hubert M, Gobbini E, Couillault C, Manh TV, Doffin AC, Berthet J, Rodriguez C, Ollion V, Kielbassa J, Sajous C, Treilleux I, Tredan O, Dubois B, Dalod M, Bendriss-Vermare N, Caux C, Valladeau-Guilemond J. Hubert M, et al. Sci Immunol. 2020 Apr 17;5(46):eaav3942. doi: 10.1126/sciimmunol.aav3942. Epub 2020 Apr 17. Sci Immunol. 2020. PMID: 32303573
Breast carcinoma cells promote the differentiation of CD34+ progenitors towards 2 different subpopulations of dendritic cells with CD1a(high)CD86(-)Langerin- and CD1a(+)CD86(+)Langerin+ phenotypes.
Thomachot MC, Bendriss-Vermare N, Massacrier C, Biota C, Treilleux I, Goddard S, Caux C, Bachelot T, Blay JY, Menetrier-Caux C. Thomachot MC, et al. Int J Cancer. 2004 Jul 10;110(5):710-20. doi: 10.1002/ijc.20146. Int J Cancer. 2004. PMID: 15146561 Free article.
ICOS-ligand expression on plasmacytoid dendritic cells supports breast cancer progression by promoting the accumulation of immunosuppressive CD4+ T cells.
Faget J, Bendriss-Vermare N, Gobert M, Durand I, Olive D, Biota C, Bachelot T, Treilleux I, Goddard-Leon S, Lavergne E, Chabaud S, Blay JY, Caux C, Ménétrier-Caux C. Faget J, et al. Cancer Res. 2012 Dec 1;72(23):6130-41. doi: 10.1158/0008-5472.CAN-12-2409. Epub 2012 Oct 1. Cancer Res. 2012. PMID: 23026134
61 results