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Benzothiazolyl and Benzoxazolyl Hydrazones Function as Zinc Metallochaperones to Reactivate Mutant p53.
J Med Chem. 2021 Feb 25;64(4):2024-2045. doi: 10.1021/acs.jmedchem.0c01360. Epub 2021 Feb 4.
J Med Chem. 2021.
PMID: 33538587
Free PMC article.
Thiosemicarbazones Functioning as Zinc Metallochaperones to Reactivate Mutant p53.
Yu X, Blanden A, Tsang AT, Zaman S, Liu Y, Gilleran J, Bencivenga AF, Kimball SD, Loh SN, Carpizo DR.
Yu X, et al. Among authors: bencivenga af.
Mol Pharmacol. 2017 Jun;91(6):567-575. doi: 10.1124/mol.116.107409. Epub 2017 Mar 20.
Mol Pharmacol. 2017.
PMID: 28320780
Free PMC article.
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Combinatorial Therapy of Zinc Metallochaperones with Mutant p53 Reactivation and Diminished Copper Binding.
Zaman S, Yu X, Bencivenga AF, Blanden AR, Liu Y, Withers T, Na B, Blayney AJ, Gilleran J, Boothman DA, Loh SN, Kimball SD, Carpizo DR.
Zaman S, et al. Among authors: bencivenga af.
Mol Cancer Ther. 2019 Aug;18(8):1355-1365. doi: 10.1158/1535-7163.MCT-18-1080. Epub 2019 Jun 13.
Mol Cancer Ther. 2019.
PMID: 31196889
Free PMC article.
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