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The FDA-approved drug Auranofin has a dual inhibitory effect on SARS-CoV-2 entry and NF-κB signaling.
Laplantine E, Chable-Bessia C, Oudin A, Swain J, Soria A, Merida P, Gourdelier M, Mestiri S, Besseghe I, Bremaud E, Neyret A, Lyonnais S, Favard C, Benaroch P, Hubert M, Schwartz O, Guerin M, Danckaert A, Del Nery E, Muriaux D, Weil R. Laplantine E, et al. Among authors: benaroch p. iScience. 2022 Oct 21;25(10):105066. doi: 10.1016/j.isci.2022.105066. Epub 2022 Sep 3. iScience. 2022. PMID: 36093378 Free PMC article.
HIV-1 Nef impairs MHC class II antigen presentation and surface expression.
Stumptner-Cuvelette P, Morchoisne S, Dugast M, Le Gall S, Raposo G, Schwartz O, Benaroch P. Stumptner-Cuvelette P, et al. Among authors: benaroch p. Proc Natl Acad Sci U S A. 2001 Oct 9;98(21):12144-9. doi: 10.1073/pnas.221256498. Epub 2001 Oct 2. Proc Natl Acad Sci U S A. 2001. PMID: 11593029 Free PMC article.
Cleavage of Toll-like receptor 3 by cathepsins B and H is essential for signaling.
Garcia-Cattaneo A, Gobert FX, Müller M, Toscano F, Flores M, Lescure A, Del Nery E, Benaroch P. Garcia-Cattaneo A, et al. Among authors: benaroch p. Proc Natl Acad Sci U S A. 2012 Jun 5;109(23):9053-8. doi: 10.1073/pnas.1115091109. Epub 2012 May 18. Proc Natl Acad Sci U S A. 2012. PMID: 22611194 Free PMC article.
HIV trafficking in host cells: motors wanted!
Gaudin R, de Alencar BC, Arhel N, Benaroch P. Gaudin R, et al. Among authors: benaroch p. Trends Cell Biol. 2013 Dec;23(12):652-62. doi: 10.1016/j.tcb.2013.09.004. Epub 2013 Oct 10. Trends Cell Biol. 2013. PMID: 24119663 Review.
How MHC class II molecules reach the endocytic pathway.
Bénaroch P, Yilla M, Raposo G, Ito K, Miwa K, Geuze HJ, Ploegh HL. Bénaroch P, et al. EMBO J. 1995 Jan 3;14(1):37-49. doi: 10.1002/j.1460-2075.1995.tb06973.x. EMBO J. 1995. PMID: 7530198 Free PMC article.
73 results