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Multiomics links global surfactant dysregulation with airflow obstruction and emphysema in COPD.
Hristova VA, Watson A, Chaerkady R, Glover MS, Ackland J, Angerman B, Belfield G, Belvisi MG, Burke H, Cellura D, Clark HW, Etal D, Freeman A, Heinson AI, Hess S, Hühn M, Hall E, Mackay A, Madsen J, McCrae C, Muthas D, Novick S, Ostridge K, Öberg L, Platt A, Postle AD, Spalluto CM, Vaarala O, Wang J, Staples KJ, Wilkinson TMA; MICA II Study group. Hristova VA, et al. Among authors: belvisi mg. ERJ Open Res. 2022 May 15;9(3):00378-2022. doi: 10.1183/23120541.00378-2022. eCollection 2023 May. ERJ Open Res. 2022. PMID: 37228288 Free PMC article.
Identification of a missense variant in SPDL1 associated with idiopathic pulmonary fibrosis.
Dhindsa RS, Mattsson J, Nag A, Wang Q, Wain LV, Allen R, Wigmore EM, Ibanez K, Vitsios D, Deevi SVV, Wasilewski S, Karlsson M, Lassi G, Olsson H, Muthas D, Monkley S, Mackay A, Murray L, Young S, Haefliger C; FinnGen Consortium; Maher TM, Belvisi MG, Jenkins G, Molyneaux PL, Platt A, Petrovski S. Dhindsa RS, et al. Among authors: belvisi mg. Commun Biol. 2021 Mar 23;4(1):392. doi: 10.1038/s42003-021-01910-y. Commun Biol. 2021. PMID: 33758299 Free PMC article.
Dysregulation of COVID-19 related gene expression in the COPD lung.
Watson A, Öberg L, Angermann B, Spalluto CM, Hühn M, Burke H, Cellura D, Freeman A, Muthas D, Etal D, Belfield G, Karlsson F, Nordström K, Ostridge K, Staples KJ, Wilkinson T; MICA II Studygroup. Watson A, et al. Respir Res. 2021 May 29;22(1):164. doi: 10.1186/s12931-021-01755-3. Respir Res. 2021. PMID: 34051791 Free PMC article.
Rare variant contribution to human disease in 281,104 UK Biobank exomes.
Wang Q, Dhindsa RS, Carss K, Harper AR, Nag A, Tachmazidou I, Vitsios D, Deevi SVV, Mackay A, Muthas D, Hühn M, Monkley S, Olsson H; AstraZeneca Genomics Initiative; Wasilewski S, Smith KR, March R, Platt A, Haefliger C, Petrovski S. Wang Q, et al. Nature. 2021 Sep;597(7877):527-532. doi: 10.1038/s41586-021-03855-y. Epub 2021 Aug 10. Nature. 2021. PMID: 34375979 Free PMC article.
Chronic lung diseases: prospects for regeneration and repair.
Barnes PJ, Anderson GP, Fagerås M, Belvisi MG. Barnes PJ, et al. Among authors: belvisi mg. Eur Respir Rev. 2021 Jan 6;30(159):200213. doi: 10.1183/16000617.0213-2020. Print 2021 Mar 31. Eur Respir Rev. 2021. PMID: 33408088 Free PMC article. Review.
Characterisation of pharmacokinetics, safety and tolerability in a first-in-human study for AZD8154, a novel inhaled selective PI3Kγδ dual inhibitor targeting airway inflammatory disease.
Sadiq MW, Asimus S, Belvisi MG, Brailsford W, Fransson R, Fuhr R, Hagberg A, Hashemi M, Jellesmark Jensen T, Jonsson J, Keen C, Körnicke T, Kristensson C, Mäenpää J, Necander S, Nemes S, Betts J. Sadiq MW, et al. Among authors: belvisi mg. Br J Clin Pharmacol. 2022 Jan;88(1):260-270. doi: 10.1111/bcp.14956. Epub 2021 Aug 8. Br J Clin Pharmacol. 2022. PMID: 34182611 Free article. Clinical Trial.
PI3Kγδ inhibition suppresses key disease features in a rat model of asthma.
Pinkerton JW, Preite S, Piras A, Zervas D, Markou T, Freeman MS, Hofving T, Ivarsson E, Bonvini SJ, Brailsford W, Yrlid L, Belvisi MG, Birrell MA. Pinkerton JW, et al. Among authors: belvisi mg. Respir Res. 2024 Apr 23;25(1):175. doi: 10.1186/s12931-024-02814-1. Respir Res. 2024. PMID: 38654248 Free PMC article.
Targeting Alveolar Repair in Idiopathic Pulmonary Fibrosis.
Ptasinski VA, Stegmayr J, Belvisi MG, Wagner DE, Murray LA. Ptasinski VA, et al. Among authors: belvisi mg. Am J Respir Cell Mol Biol. 2021 Oct;65(4):347-365. doi: 10.1165/rcmb.2020-0476TR. Am J Respir Cell Mol Biol. 2021. PMID: 34129811 Free PMC article. Review.
224 results