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Mutations in S-adenosylhomocysteine hydrolase (AHCY) affect its nucleocytoplasmic distribution and capability to interact with S-adenosylhomocysteine hydrolase-like 1 protein.
Grbeša I, Kalo A, Belužić R, Kovačević L, Lepur A, Rokić F, Hochberg H, Kanter I, Simunović V, Muńoz-Torres PM, Shav-Tal Y, Vugrek O. Grbeša I, et al. Among authors: beluzic r. Eur J Cell Biol. 2017 Sep;96(6):579-590. doi: 10.1016/j.ejcb.2017.05.002. Epub 2017 May 13. Eur J Cell Biol. 2017. PMID: 28647132
De novo expression of transfected sirtuin 3 enhances susceptibility of human MCF-7 breast cancer cells to hyperoxia treatment.
Pinterić M, Podgorski II, Sobočanec S, Popović Hadžija M, Paradžik M, Dekanić A, Marinović M, Halasz M, Belužić R, Davidović G, Ambriović Ristov A, Balog T. Pinterić M, et al. Among authors: beluzic r. Free Radic Res. 2018 Jun;52(6):672-684. doi: 10.1080/10715762.2018.1462495. Epub 2018 Apr 23. Free Radic Res. 2018. PMID: 29683756
S-Adenosylhomocysteine hydrolase (AdoHcyase) deficiency: enzymatic capabilities of human AdoHcyase are highly effected by changes to codon 89 and its surrounding residues.
Beluzić R, Cuk M, Pavkov T, Barić I, Vugrek O. Beluzić R, et al. Biochem Biophys Res Commun. 2008 Mar 28;368(1):30-6. doi: 10.1016/j.bbrc.2008.01.042. Epub 2008 Jan 22. Biochem Biophys Res Commun. 2008. PMID: 18211827
Two missense mutations in codons 89 (A>V) and 143 (Y>C) in the AdoHcyase gene were identified [N.R.M. Buist, B. Glenn, O. Vugrek, C. Wagner, S. Stabler, R.H. Allen, I. ...Accordingly, we have proven the Y143C mutation to be highly inactivating [R. Be
Two missense mutations in codons 89 (A>V) and 143 (Y>C) in the AdoHcyase gene were identified [N.R.M. Buist, B. Glenn, O. Vugre …
18 results