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From sequence to molecular pathology, and a mechanism driving the neuroendocrine phenotype in prostate cancer.
Lapuk AV, Wu C, Wyatt AW, McPherson A, McConeghy BJ, Brahmbhatt S, Mo F, Zoubeidi A, Anderson S, Bell RH, Haegert A, Shukin R, Wang Y, Fazli L, Hurtado-Coll A, Jones EC, Hach F, Hormozdiari F, Hajirasouliha I, Boutros PC, Bristow RG, Zhao Y, Marra MA, Fanjul A, Maher CA, Chinnaiyan AM, Rubin MA, Beltran H, Sahinalp SC, Gleave ME, Volik SV, Collins CC. Lapuk AV, et al. Among authors: beltran h. J Pathol. 2012 Jul;227(3):286-97. doi: 10.1002/path.4047. J Pathol. 2012. PMID: 22553170 Free PMC article.
The Placental Gene PEG10 Promotes Progression of Neuroendocrine Prostate Cancer.
Akamatsu S, Wyatt AW, Lin D, Lysakowski S, Zhang F, Kim S, Tse C, Wang K, Mo F, Haegert A, Brahmbhatt S, Bell R, Adomat H, Kawai Y, Xue H, Dong X, Fazli L, Tsai H, Lotan TL, Kossai M, Mosquera JM, Rubin MA, Beltran H, Zoubeidi A, Wang Y, Gleave ME, Collins CC. Akamatsu S, et al. Among authors: beltran h. Cell Rep. 2015 Aug 11;12(6):922-36. doi: 10.1016/j.celrep.2015.07.012. Epub 2015 Jul 30. Cell Rep. 2015. PMID: 26235627 Free article.
The Master Neural Transcription Factor BRN2 Is an Androgen Receptor-Suppressed Driver of Neuroendocrine Differentiation in Prostate Cancer.
Bishop JL, Thaper D, Vahid S, Davies A, Ketola K, Kuruma H, Jama R, Nip KM, Angeles A, Johnson F, Wyatt AW, Fazli L, Gleave ME, Lin D, Rubin MA, Collins CC, Wang Y, Beltran H, Zoubeidi A. Bishop JL, et al. Among authors: beltran h. Cancer Discov. 2017 Jan;7(1):54-71. doi: 10.1158/2159-8290.CD-15-1263. Epub 2016 Oct 26. Cancer Discov. 2017. PMID: 27784708
The long noncoding RNA landscape of neuroendocrine prostate cancer and its clinical implications.
Ramnarine VR, Alshalalfa M, Mo F, Nabavi N, Erho N, Takhar M, Shukin R, Brahmbhatt S, Gawronski A, Kobelev M, Nouri M, Lin D, Tsai H, Lotan TL, Karnes RJ, Rubin MA, Zoubeidi A, Gleave ME, Sahinalp C, Wyatt AW, Volik SV, Beltran H, Davicioni E, Wang Y, Collins CC. Ramnarine VR, et al. Among authors: beltran h. Gigascience. 2018 Jun 1;7(6):giy050. doi: 10.1093/gigascience/giy050. Gigascience. 2018. PMID: 29757368 Free PMC article.
ONECUT2 is a driver of neuroendocrine prostate cancer.
Guo H, Ci X, Ahmed M, Hua JT, Soares F, Lin D, Puca L, Vosoughi A, Xue H, Li E, Su P, Chen S, Nguyen T, Liang Y, Zhang Y, Xu X, Xu J, Sheahan AV, Ba-Alawi W, Zhang S, Mahamud O, Vellanki RN, Gleave M, Bristow RG, Haibe-Kains B, Poirier JT, Rudin CM, Tsao MS, Wouters BG, Fazli L, Feng FY, Ellis L, van der Kwast T, Berlin A, Koritzinsky M, Boutros PC, Zoubeidi A, Beltran H, Wang Y, He HH. Guo H, et al. Among authors: beltran h. Nat Commun. 2019 Jan 17;10(1):278. doi: 10.1038/s41467-018-08133-6. Nat Commun. 2019. PMID: 30655535 Free PMC article.
Biological Evolution of Castration-resistant Prostate Cancer.
Davies A, Conteduca V, Zoubeidi A, Beltran H. Davies A, et al. Among authors: beltran h. Eur Urol Focus. 2019 Mar;5(2):147-154. doi: 10.1016/j.euf.2019.01.016. Epub 2019 Feb 14. Eur Urol Focus. 2019. PMID: 30772358 Review.
The Role of Lineage Plasticity in Prostate Cancer Therapy Resistance.
Beltran H, Hruszkewycz A, Scher HI, Hildesheim J, Isaacs J, Yu EY, Kelly K, Lin D, Dicker A, Arnold J, Hecht T, Wicha M, Sears R, Rowley D, White R, Gulley JL, Lee J, Diaz Meco M, Small EJ, Shen M, Knudsen K, Goodrich DW, Lotan T, Zoubeidi A, Sawyers CL, Rudin CM, Loda M, Thompson T, Rubin MA, Tawab-Amiri A, Dahut W, Nelson PS. Beltran H, et al. Clin Cancer Res. 2019 Dec 1;25(23):6916-6924. doi: 10.1158/1078-0432.CCR-19-1423. Epub 2019 Jul 30. Clin Cancer Res. 2019. PMID: 31363002 Free PMC article.
260 results