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Application of AOPs to assist regulatory assessment of chemical risks - Case studies, needs and recommendations.
Bajard L, Adamovsky O, Audouze K, Baken K, Barouki R, Beltman JB, Beronius A, Bonefeld-Jørgensen EC, Cano-Sancho G, de Baat ML, Di Tillio F, Fernández MF, FitzGerald RE, Gundacker C, Hernández AF, Hilscherova K, Karakitsios S, Kuchovska E, Long M, Luijten M, Majid S, Marx-Stoelting P, Mustieles V, Negi CK, Sarigiannis D, Scholz S, Sovadinova I, Stierum R, Tanabe S, Tollefsen KE, van den Brand AD, Vogs C, Wielsøe M, Wittwehr C, Blaha L. Bajard L, et al. Among authors: beltman jb. Environ Res. 2023 Jan 15;217:114650. doi: 10.1016/j.envres.2022.114650. Epub 2022 Oct 27. Environ Res. 2023. PMID: 36309218 Free PMC article. Review.
DRAG in situ barcoding reveals an increased number of HSPCs contributing to myelopoiesis with age.
Urbanus J, Cosgrove J, Beltman JB, Elhanati Y, Moral RA, Conrad C, van Heijst JW, Tubeuf E, Velds A, Kok L, Merle C, Magnusson JP, Guyonnet L, Frisén J, Fre S, Walczak AM, Mora T, Jacobs H, Schumacher TN, Perié L. Urbanus J, et al. Among authors: beltman jb. Nat Commun. 2023 Apr 17;14(1):2184. doi: 10.1038/s41467-023-37167-8. Nat Commun. 2023. PMID: 37069150 Free PMC article.
Model-based translation of DNA damage signaling dynamics across cell types.
Heldring MM, Wijaya LS, Niemeijer M, Yang H, Lakhal T, Le Dévédec SE, van de Water B, Beltman JB. Heldring MM, et al. Among authors: beltman jb. PLoS Comput Biol. 2022 Jul 8;18(7):e1010264. doi: 10.1371/journal.pcbi.1010264. eCollection 2022 Jul. PLoS Comput Biol. 2022. PMID: 35802572 Free PMC article.
Dynamic modeling of Nrf2 pathway activation in liver cells after toxicant exposure.
Hiemstra S, Fehling-Kaschek M, Kuijper IA, Bischoff LJM, Wijaya LS, Rosenblatt M, Esselink J, van Egmond A, Mos J, Beltman JB, Timmer J, van de Water B, Kaschek D. Hiemstra S, et al. Among authors: beltman jb. Sci Rep. 2022 May 5;12(1):7336. doi: 10.1038/s41598-022-10857-x. Sci Rep. 2022. PMID: 35513409 Free PMC article.
49 results