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Discovery of the 2-phenyl-4,5,6,7-Tetrahydro-1H-indole as a novel anti-hepatitis C virus targeting scaffold.
Andreev IA, Manvar D, Barreca ML, Belov DS, Basu A, Sweeney NL, Ratmanova NK, Lukyanenko ER, Manfroni G, Cecchetti V, Frick DN, Altieri A, Kaushik-Basu N, Kurkin AV. Andreev IA, et al. Among authors: belov ds. Eur J Med Chem. 2015;96:250-8. doi: 10.1016/j.ejmech.2015.04.022. Epub 2015 Apr 10. Eur J Med Chem. 2015. PMID: 25890075 Free PMC article.
Structure-based lead optimization to improve antiviral potency and ADMET properties of phenyl-1H-pyrrole-carboxamide entry inhibitors targeted to HIV-1 gp120.
Curreli F, Belov DS, Kwon YD, Ramesh R, Furimsky AM, O'Loughlin K, Byrge PC, Iyer LV, Mirsalis JC, Kurkin AV, Altieri A, Debnath AK. Curreli F, et al. Among authors: belov ds. Eur J Med Chem. 2018 Jun 25;154:367-391. doi: 10.1016/j.ejmech.2018.04.062. Epub 2018 May 12. Eur J Med Chem. 2018. PMID: 29860061 Free PMC article.
Preclinical Optimization of gp120 Entry Antagonists as anti-HIV-1 Agents with Improved Cytotoxicity and ADME Properties through Rational Design, Synthesis, and Antiviral Evaluation.
Curreli F, Ahmed S, Benedict Victor SM, Iusupov IR, Belov DS, Markov PO, Kurkin AV, Altieri A, Debnath AK. Curreli F, et al. Among authors: belov ds. J Med Chem. 2020 Feb 27;63(4):1724-1749. doi: 10.1021/acs.jmedchem.9b02149. Epub 2020 Feb 17. J Med Chem. 2020. PMID: 32031803 Free PMC article.
Bicyclic octahydrocyclohepta[b]pyrrol-4(1H)one derivatives as novel selective anti-hepatitis C virus agents.
Kaushik-Basu N, Ratmanova NK, Manvar D, Belov DS, Cevik O, Basu A, Yerukhimovich MM, Lukyanenko ER, Andreev IA, Belov GM, Manfroni G, Cecchetti V, Frick DN, Kurkin AV, Altieri A, Barreca ML. Kaushik-Basu N, et al. Among authors: belov gm, belov ds. Eur J Med Chem. 2016 Oct 21;122:319-325. doi: 10.1016/j.ejmech.2016.06.041. Epub 2016 Jun 23. Eur J Med Chem. 2016. PMID: 27376494
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