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Generation of two human induced pluripotent stem cell lines, LUMCi020-A and LUMCi021-A, from two patients with Catecholaminergic Polymorphic Ventricular Tachycardia carrying heterozygous mutations in the RYR2 gene.
Meraviglia V, Arendzen CH, Freund C, Atsma DE, Mummery CL, Bellin M. Meraviglia V, et al. Among authors: bellin m. Stem Cell Res. 2020 May;45:101764. doi: 10.1016/j.scr.2020.101764. Epub 2020 Apr 8. Stem Cell Res. 2020. PMID: 32315959 Free article.
Human-iPSC-Derived Cardiac Stromal Cells Enhance Maturation in 3D Cardiac Microtissues and Reveal Non-cardiomyocyte Contributions to Heart Disease.
Giacomelli E, Meraviglia V, Campostrini G, Cochrane A, Cao X, van Helden RWJ, Krotenberg Garcia A, Mircea M, Kostidis S, Davis RP, van Meer BJ, Jost CR, Koster AJ, Mei H, Míguez DG, Mulder AA, Ledesma-Terrón M, Pompilio G, Sala L, Salvatori DCF, Slieker RC, Sommariva E, de Vries AAF, Giera M, Semrau S, Tertoolen LGJ, Orlova VV, Bellin M, Mummery CL. Giacomelli E, et al. Among authors: bellin m. Cell Stem Cell. 2020 Jun 4;26(6):862-879.e11. doi: 10.1016/j.stem.2020.05.004. Epub 2020 May 26. Cell Stem Cell. 2020. PMID: 32459996 Free PMC article.
Generation of human induced pluripotent stem cell line LUMCi027-A and its isogenic gene-corrected line from a patient affected by arrhythmogenic cardiomyopathy and carrying the c.2013delC PKP2 mutation.
Meraviglia V, Arendzen CH, Tok M, Freund C, Maione AS, Sommariva E, Bellin M. Meraviglia V, et al. Among authors: bellin m. Stem Cell Res. 2020 Jul;46:101835. doi: 10.1016/j.scr.2020.101835. Epub 2020 May 5. Stem Cell Res. 2020. PMID: 32485643 Free article.
Generation of human induced pluripotent stem cell line EURACi006-A and its isogenic gene-corrected line EURACi006-A-1 from an arrhythmogenic cardiomyopathy patient carrying the c.1643delG PKP2 mutation.
Meraviglia V, Ganesh S, Arendzen CH, Freund C, Sommariva E, Rossini A, Bellin M. Meraviglia V, et al. Among authors: bellin m. Stem Cell Res. 2021 Jul;54:102426. doi: 10.1016/j.scr.2021.102426. Epub 2021 Jun 8. Stem Cell Res. 2021. PMID: 34134068 Free article.
Dantrolene rescues arrhythmogenic RYR2 defect in a patient-specific stem cell model of catecholaminergic polymorphic ventricular tachycardia.
Jung CB, Moretti A, Mederos y Schnitzler M, Iop L, Storch U, Bellin M, Dorn T, Ruppenthal S, Pfeiffer S, Goedel A, Dirschinger RJ, Seyfarth M, Lam JT, Sinnecker D, Gudermann T, Lipp P, Laugwitz KL. Jung CB, et al. Among authors: bellin m. EMBO Mol Med. 2012 Mar;4(3):180-91. doi: 10.1002/emmm.201100194. Epub 2012 Jan 25. EMBO Mol Med. 2012. PMID: 22174035 Free PMC article.
542 results