Bell TA 3rd - Search Results

1

Glis2 is an early effector of polycystin signaling and a target for therapy in polycystic kidney disease.

Zhang C, Rehman M, Tian X, Pei SLC, Gu J, Bell TA 3rd, Dong K, Tham MS, Cai Y, Wei Z, Behrens F, Jetten AM, Zhao H, Lek M, Somlo S. Zhang C, et al. Among authors: bell ta 3rd. Nat Commun. 2024 May 1;15(1):3698. doi: 10.1038/s41467-024-48025-6. Nat Commun. 2024. PMID: 38693102 Free PMC article.

2

Inhibition of asparagine synthetase effectively retards polycystic kidney disease progression.

Clerici S, Podrini C, Stefanoni D, Distefano G, Cassina L, Steidl ME, Tronci L, Canu T, Chiaravalli M, Spies D, Bell TA 3rd, Costa AS, Esposito A, D'Alessandro A, Frezza C, Bachi A, Boletta A. Clerici S, et al. Among authors: bell ta 3rd. EMBO Mol Med. 2024 Apr 29. doi: 10.1038/s44321-024-00071-9. Online ahead of print. EMBO Mol Med. 2024. PMID: 38684863 Free article.

3

Antisense Oligonucleotide-Mediated Silencing of Mitochondrial Fusion and Fission Factors Modulates Mitochondrial Dynamics and Rescues Mitochondrial Dysfunction.

Garcia DA, Powers AF, Bell TA 3rd, Guo S, Aghajan M. Garcia DA, et al. Among authors: bell ta 3rd. Nucleic Acid Ther. 2022 Feb;32(1):51-65. doi: 10.1089/nat.2021.0029. Epub 2021 Oct 25. Nucleic Acid Ther. 2022. PMID: 34698563 Free PMC article.

4

Antisense oligonucleotide-mediated inhibition of angiopoietin-like protein 3 increases reverse cholesterol transport in mice.

Bell TA 3rd, Liu M, Donner AJ, Lee RG, Mullick AE, Crooke RM. Bell TA 3rd, et al. J Lipid Res. 2021;62:100101. doi: 10.1016/j.jlr.2021.100101. Epub 2021 Aug 6. J Lipid Res. 2021. PMID: 34371033 Free PMC article.

5

Chemical modification of PS-ASO therapeutics reduces cellular protein-binding and improves the therapeutic index.

Shen W, De Hoyos CL, Migawa MT, Vickers TA, Sun H, Low A, Bell TA 3rd, Rahdar M, Mukhopadhyay S, Hart CE, Bell M, Riney S, Murray SF, Greenlee S, Crooke RM, Liang XH, Seth PP, Crooke ST. Shen W, et al. Among authors: bell ta 3rd. Nat Biotechnol. 2019 Jun;37(6):640-650. doi: 10.1038/s41587-019-0106-2. Epub 2019 Apr 29. Nat Biotechnol. 2019. PMID: 31036929

6

Antisense oligonucleotide inhibition of cholesteryl ester transfer protein enhances RCT in hyperlipidemic, CETP transgenic, LDLr-/- mice.

Bell TA 3rd, Graham MJ, Lee RG, Mullick AE, Fu W, Norris D, Crooke RM. Bell TA 3rd, et al. J Lipid Res. 2013 Oct;54(10):2647-57. doi: 10.1194/jlr.M036509. Epub 2013 Jun 25. J Lipid Res. 2013. PMID: 23801661 Free PMC article.

7

Antisense oligonucleotide inhibition of apolipoprotein C-III reduces plasma triglycerides in rodents, nonhuman primates, and humans.

Graham MJ, Lee RG, Bell TA 3rd, Fu W, Mullick AE, Alexander VJ, Singleton W, Viney N, Geary R, Su J, Baker BF, Burkey J, Crooke ST, Crooke RM. Graham MJ, et al. Among authors: bell ta 3rd. Circ Res. 2013 May 24;112(11):1479-90. doi: 10.1161/CIRCRESAHA.111.300367. Epub 2013 Mar 29. Circ Res. 2013. PMID: 23542898 Clinical Trial.

8

Targeted depletion of hepatic ACAT2-driven cholesterol esterification reveals a non-biliary route for fecal neutral sterol loss.

Brown JM, Bell TA 3rd, Alger HM, Sawyer JK, Smith TL, Kelley K, Shah R, Wilson MD, Davis MA, Lee RG, Graham MJ, Crooke RM, Rudel LL. Brown JM, et al. Among authors: bell ta 3rd. J Biol Chem. 2008 Apr 18;283(16):10522-34. doi: 10.1074/jbc.M707659200. Epub 2008 Feb 14. J Biol Chem. 2008. PMID: 18281279 Free PMC article.

9

Increased endothelial expression of Toll-like receptor 2 at sites of disturbed blood flow exacerbates early atherogenic events.

Mullick AE, Soldau K, Kiosses WB, Bell TA 3rd, Tobias PS, Curtiss LK. Mullick AE, et al. Among authors: bell ta 3rd. J Exp Med. 2008 Feb 18;205(2):373-83. doi: 10.1084/jem.20071096. Epub 2008 Feb 4. J Exp Med. 2008. PMID: 18250194 Free PMC article.

10

Dietary fat-induced alterations in atherosclerosis are abolished by ACAT2-deficiency in ApoB100 only, LDLr-/- mice.

Bell TA 3rd, Kelley K, Wilson MD, Sawyer JK, Rudel LL. Bell TA 3rd, et al. Arterioscler Thromb Vasc Biol. 2007 Jun;27(6):1396-402. doi: 10.1161/ATVBAHA.107.142802. Epub 2007 Apr 12. Arterioscler Thromb Vasc Biol. 2007. PMID: 17431188

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