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Page 1
Obesity-Linked PPARγ S273 Phosphorylation Promotes Insulin Resistance through Growth Differentiation Factor 3.
Hall JA, Ramachandran D, Roh HC, DiSpirito JR, Belchior T, Zushin PH, Palmer C, Hong S, Mina AI, Liu B, Deng Z, Aryal P, Jacobs C, Tenen D, Brown CW, Charles JF, Shulman GI, Kahn BB, Tsai LTY, Rosen ED, Spiegelman BM, Banks AS. Hall JA, et al. Among authors: belchior t. Cell Metab. 2020 Oct 6;32(4):665-675.e6. doi: 10.1016/j.cmet.2020.08.016. Epub 2020 Sep 16. Cell Metab. 2020. PMID: 32941798 Free PMC article.
Dectin-1 Activation Exacerbates Obesity and Insulin Resistance in the Absence of MyD88.
Castoldi A, Andrade-Oliveira V, Aguiar CF, Amano MT, Lee J, Miyagi MT, Latância MT, Braga TT, da Silva MB, Ignácio A, Carola Correia Lima JD, Loures FV, Albuquerque JAT, Macêdo MB, Almeida RR, Gaiarsa JW, Luévano-Martínez LA, Belchior T, Hiyane MI, Brown GD, Mori MA, Hoffmann C, Seelaender M, Festuccia WT, Moraes-Vieira PM, Câmara NOS. Castoldi A, et al. Among authors: belchior t. Cell Rep. 2017 Jun 13;19(11):2272-2288. doi: 10.1016/j.celrep.2017.05.059. Cell Rep. 2017. PMID: 28614714 Free PMC article.
PPARγ-induced upregulation of subcutaneous fat adiponectin secretion, glyceroneogenesis and BCAA oxidation requires mTORC1 activity.
Andrade ML, Gilio GR, Perandini LA, Peixoto AS, Moreno MF, Castro É, Oliveira TE, Vieira TS, Ortiz-Silva M, Thomazelli CA, Chaves-Filho AB, Belchior T, Chimin P, Magdalon J, Ivison R, Pant D, Tsai L, Yoshinaga MY, Miyamoto S, Festuccia WT. Andrade ML, et al. Among authors: belchior t. Biochim Biophys Acta Mol Cell Biol Lipids. 2021 Aug;1866(8):158967. doi: 10.1016/j.bbalip.2021.158967. Epub 2021 May 15. Biochim Biophys Acta Mol Cell Biol Lipids. 2021. PMID: 34004356 Free PMC article.
Palmitoleic acid reduces high fat diet-induced liver inflammation by promoting PPAR-γ-independent M2a polarization of myeloid cells.
Souza CO, Teixeira AAS, Biondo LA, Silveira LS, de Souza Breda CN, Braga TT, Camara NOS, Belchior T, Festuccia WT, Diniz TA, Ferreira GM, Hirata MH, Chaves-Filho AB, Yoshinaga MY, Miyamoto S, Calder PC, Sethi JK, Rosa Neto JC. Souza CO, et al. Among authors: belchior t. Biochim Biophys Acta Mol Cell Biol Lipids. 2020 Oct;1865(10):158776. doi: 10.1016/j.bbalip.2020.158776. Epub 2020 Jul 30. Biochim Biophys Acta Mol Cell Biol Lipids. 2020. PMID: 32738301 Free PMC article.
Constitutive Activation of the Nutrient Sensor mTORC1 in Myeloid Cells Induced by Tsc1 Deletion Protects Mice from Diet-Induced Obesity.
Paschoal VA, Belchior T, Amano MT, Burgos-Silva M, Peixoto AS, Magdalon J, Vieira TS, Andrade ML, Moreno MF, Chimin P, Câmara NO, Festuccia WT. Paschoal VA, et al. Among authors: belchior t. Mol Nutr Food Res. 2018 Sep;62(17):e1800283. doi: 10.1002/mnfr.201800283. Epub 2018 Aug 8. Mol Nutr Food Res. 2018. PMID: 30001482
mTORC1 inhibition with rapamycin exacerbates adipose tissue inflammation in obese mice and dissociates macrophage phenotype from function.
Paschoal VA, Amano MT, Belchior T, Magdalon J, Chimin P, Andrade ML, Ortiz-Silva M, Castro É, Yamashita AS, Rosa Neto JC, Câmara NO, Festuccia WT. Paschoal VA, et al. Among authors: belchior t. Immunobiology. 2017 Feb;222(2):261-271. doi: 10.1016/j.imbio.2016.09.014. Epub 2016 Sep 28. Immunobiology. 2017. PMID: 27692982
Adipocyte mTORC1 deficiency promotes adipose tissue inflammation and NLRP3 inflammasome activation via oxidative stress and de novo ceramide synthesis.
Chimin P, Andrade ML, Belchior T, Paschoal VA, Magdalon J, Yamashita AS, Castro É, Castoldi A, Chaves-Filho AB, Yoshinaga MY, Miyamoto S, Câmara NO, Festuccia WT. Chimin P, et al. Among authors: belchior t. J Lipid Res. 2017 Sep;58(9):1797-1807. doi: 10.1194/jlr.M074518. Epub 2017 Jul 5. J Lipid Res. 2017. PMID: 28679588 Free PMC article.
Omega-3 fatty acids protect from diet-induced obesity, glucose intolerance, and adipose tissue inflammation through PPARγ-dependent and PPARγ-independent actions.
Belchior T, Paschoal VA, Magdalon J, Chimin P, Farias TM, Chaves-Filho AB, Gorjão R, St-Pierre P, Miyamoto S, Kang JX, Deshaies Y, Marette A, Festuccia W. Belchior T, et al. Mol Nutr Food Res. 2015 May;59(5):957-67. doi: 10.1002/mnfr.201400914. Epub 2015 Mar 16. Mol Nutr Food Res. 2015. PMID: 25641959
Fish Oil Protects Wild Type and Uncoupling Protein 1-Deficient Mice from Obesity and Glucose Intolerance by Increasing Energy Expenditure.
Oliveira TE, Castro É, Belchior T, Andrade ML, Chaves-Filho AB, Peixoto AS, Moreno MF, Ortiz-Silva M, Moreira RJ, Inague A, Yoshinaga MY, Miyamoto S, Moustaid-Moussa N, Festuccia WT. Oliveira TE, et al. Among authors: belchior t. Mol Nutr Food Res. 2019 Apr;63(7):e1800813. doi: 10.1002/mnfr.201800813. Epub 2019 Jan 17. Mol Nutr Food Res. 2019. PMID: 30632684
Constitutive adipocyte mTORC1 activation enhances mitochondrial activity and reduces visceral adiposity in mice.
Magdalon J, Chimin P, Belchior T, Neves RX, Vieira-Lara MA, Andrade ML, Farias TS, Bolsoni-Lopes A, Paschoal VA, Yamashita AS, Kowaltowski AJ, Festuccia WT. Magdalon J, et al. Among authors: belchior t. Biochim Biophys Acta. 2016 May;1861(5):430-8. doi: 10.1016/j.bbalip.2016.02.023. Epub 2016 Feb 27. Biochim Biophys Acta. 2016. PMID: 26923434
21 results