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Treatment with siRNAs is commonly associated with GPX4 up-regulation and target knockdown-independent sensitization to ferroptosis.
von Mässenhausen A, Schlecht MN, Beer K, Maremonti F, Tonnus W, Belavgeni A, Gavali S, Flade K, Riley JS, Zamora Gonzalez N, Brucker A, Becker JN, Tmava M, Meyer C, Peitzsch M, Hugo C, Gembardt F, Angeli JPF, Bornstein SR, Tait SWG, Linkermann A. von Mässenhausen A, et al. Among authors: belavgeni a. Sci Adv. 2024 Mar 15;10(11):eadk7329. doi: 10.1126/sciadv.adk7329. Epub 2024 Mar 15. Sci Adv. 2024. PMID: 38489367 Free PMC article.
vPIF-1 is an insulin-like antiferroptotic viral peptide.
Belavgeni A, Maremonti F, Tonnus W, Stadtmüller M, Gavali S, Mallais M, Flade K, Brucker A, Becker JN, Beer K, Tmava M, Stumpf J, Gembardt F, Hugo C, Giacca M, Hale BG, Perakakis N, Sha W, Pratt DA, Schally AV, Bornstein SR, Linkermann A. Belavgeni A, et al. Proc Natl Acad Sci U S A. 2023 May 23;120(21):e2300320120. doi: 10.1073/pnas.2300320120. Epub 2023 May 15. Proc Natl Acad Sci U S A. 2023. PMID: 37186845 Free PMC article.
Gasdermin D-deficient mice are hypersensitive to acute kidney injury.
Tonnus W, Maremonti F, Belavgeni A, Latk M, Kusunoki Y, Brucker A, von Mässenhausen A, Meyer C, Locke S, Gembardt F, Beer K, Hoppenz P, Becker JU, Hugo C, Anders HJ, Bornstein SR, Shao F, Linkermann A. Tonnus W, et al. Among authors: belavgeni a. Cell Death Dis. 2022 Sep 15;13(9):792. doi: 10.1038/s41419-022-05230-9. Cell Death Dis. 2022. PMID: 36109515 Free PMC article.
Schwann cell necroptosis in diabetic neuropathy.
Belavgeni A, Maremonti F, Stadtmüller M, Bornstein SR, Linkermann A. Belavgeni A, et al. Proc Natl Acad Sci U S A. 2022 Apr 26;119(17):e2204049119. doi: 10.1073/pnas.2204049119. Epub 2022 Apr 21. Proc Natl Acad Sci U S A. 2022. PMID: 35446622 Free PMC article. No abstract available.
COVID-19 and Diabetic Nephropathy.
Maremonti F, Locke S, Tonnus W, Beer K, Brucker A, Gonzalez NZ, Latk M, Belavgeni A, Hoppenz P, Hugo C, Linkermann A. Maremonti F, et al. Among authors: belavgeni a. Horm Metab Res. 2022 Aug;54(8):510-513. doi: 10.1055/a-1819-4822. Epub 2022 Apr 6. Horm Metab Res. 2022. PMID: 35388439
Dexamethasone sensitizes to ferroptosis by glucocorticoid receptor-induced dipeptidase-1 expression and glutathione depletion.
von Mässenhausen A, Zamora Gonzalez N, Maremonti F, Belavgeni A, Tonnus W, Meyer C, Beer K, Hannani MT, Lau A, Peitzsch M, Hoppenz P, Locke S, Chavakis T, Kramann R, Muruve DA, Hugo C, Bornstein SR, Linkermann A. von Mässenhausen A, et al. Among authors: belavgeni a. Sci Adv. 2022 Feb 4;8(5):eabl8920. doi: 10.1126/sciadv.abl8920. Epub 2022 Feb 2. Sci Adv. 2022. PMID: 35108055 Free PMC article.
Dysfunction of the key ferroptosis-surveilling systems hypersensitizes mice to tubular necrosis during acute kidney injury.
Tonnus W, Meyer C, Steinebach C, Belavgeni A, von Mässenhausen A, Gonzalez NZ, Maremonti F, Gembardt F, Himmerkus N, Latk M, Locke S, Marschner J, Li W, Short S, Doll S, Ingold I, Proneth B, Daniel C, Kabgani N, Kramann R, Motika S, Hergenrother PJ, Bornstein SR, Hugo C, Becker JU, Amann K, Anders HJ, Kreisel D, Pratt D, Gütschow M, Conrad M, Linkermann A. Tonnus W, et al. Among authors: belavgeni a. Nat Commun. 2021 Jul 20;12(1):4402. doi: 10.1038/s41467-021-24712-6. Nat Commun. 2021. PMID: 34285231 Free PMC article.
The role of regulated necrosis in endocrine diseases.
Tonnus W, Belavgeni A, Beuschlein F, Eisenhofer G, Fassnacht M, Kroiss M, Krone NP, Reincke M, Bornstein SR, Linkermann A. Tonnus W, et al. Among authors: belavgeni a. Nat Rev Endocrinol. 2021 Aug;17(8):497-510. doi: 10.1038/s41574-021-00499-w. Epub 2021 Jun 16. Nat Rev Endocrinol. 2021. PMID: 34135504 Free PMC article. Review.
22 results