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Phosphorylation of murine SAMHD1 regulates its antiretroviral activity.
Wittmann S, Behrendt R, Eissmann K, Volkmann B, Thomas D, Ebert T, Cribier A, Benkirane M, Hornung V, Bouzas NF, Gramberg T. Wittmann S, et al. Among authors: behrendt r. Retrovirology. 2015 Dec 15;12:103. doi: 10.1186/s12977-015-0229-6. Retrovirology. 2015. PMID: 26667483 Free PMC article.
Mouse SAMHD1 has antiretroviral activity and suppresses a spontaneous cell-intrinsic antiviral response.
Behrendt R, Schumann T, Gerbaulet A, Nguyen LA, Schubert N, Alexopoulou D, Berka U, Lienenklaus S, Peschke K, Gibbert K, Wittmann S, Lindemann D, Weiss S, Dahl A, Naumann R, Dittmer U, Kim B, Mueller W, Gramberg T, Roers A. Behrendt R, et al. Cell Rep. 2013 Aug 29;4(4):689-96. doi: 10.1016/j.celrep.2013.07.037. Epub 2013 Aug 22. Cell Rep. 2013. PMID: 23972988 Free PMC article.
Genome Replication Is Associated With Release of Immunogenic DNA Waste.
Schubert N, Schumann T, Daum E, Flade K, Ge Y, Hagedorn L, Edelmann W, Müller L, Schmitz M, Kuut G, Hornung V, Behrendt R, Roers A. Schubert N, et al. Among authors: behrendt r. Front Immunol. 2022 May 11;13:880413. doi: 10.3389/fimmu.2022.880413. eCollection 2022. Front Immunol. 2022. PMID: 35634291 Free PMC article.
Deficiency for SAMHD1 activates MDA5 in a cGAS/STING-dependent manner.
Schumann T, Ramon SC, Schubert N, Mayo MA, Hega M, Maser KI, Ada SR, Sydow L, Hajikazemi M, Badstübner M, Müller P, Ge Y, Shakeri F, Buness A, Rupf B, Lienenklaus S, Utess B, Muhandes L, Haase M, Rupp L, Schmitz M, Gramberg T, Manel N, Hartmann G, Zillinger T, Kato H, Bauer S, Gerbaulet A, Paeschke K, Roers A, Behrendt R. Schumann T, et al. Among authors: behrendt r. J Exp Med. 2023 Jan 2;220(1):e20220829. doi: 10.1084/jem.20220829. Epub 2022 Nov 8. J Exp Med. 2023. PMID: 36346347 Free PMC article.
Lack of Trex1 Causes Systemic Autoimmunity despite the Presence of Antiretroviral Drugs.
Achleitner M, Kleefisch M, Hennig A, Peschke K, Polikarpova A, Oertel R, Gabriel B, Schulze L, Lindeman D, Gerbaulet A, Fiebig U, Lee-Kirsch MA, Roers A, Behrendt R. Achleitner M, et al. Among authors: behrendt r. J Immunol. 2017 Oct 1;199(7):2261-2269. doi: 10.4049/jimmunol.1700714. Epub 2017 Aug 23. J Immunol. 2017. PMID: 28835460
Loss of Trex1 in Dendritic Cells Is Sufficient To Trigger Systemic Autoimmunity.
Peschke K, Achleitner M, Frenzel K, Gerbaulet A, Ada SR, Zeller N, Lienenklaus S, Lesche M, Poulet C, Naumann R, Dahl A, Ravens U, Günther C, Müller W, Knobeloch KP, Prinz M, Roers A, Behrendt R. Peschke K, et al. Among authors: behrendt r. J Immunol. 2016 Sep 15;197(6):2157-66. doi: 10.4049/jimmunol.1600722. Epub 2016 Aug 10. J Immunol. 2016. PMID: 27511730
90 results