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Epoxygenase inactivation exacerbates diet and aging-associated metabolic dysfunction resulting from impaired adipogenesis.
Olona A, Terra X, Ko JH, Grau-Bové C, Pinent M, Ardevol A, Diaz AG, Moreno-Moral A, Edin M, Bishop-Bailey D, Zeldin DC, Aitman TJ, Petretto E, Blay M, Behmoaras J. Olona A, et al. Among authors: behmoaras j. Mol Metab. 2018 May;11:18-32. doi: 10.1016/j.molmet.2018.03.003. Epub 2018 Mar 9. Mol Metab. 2018. PMID: 29656108 Free PMC article.
Cardiac glycosides are broad-spectrum senolytics.
Guerrero A, Herranz N, Sun B, Wagner V, Gallage S, Guiho R, Wolter K, Pombo J, Irvine EE, Innes AJ, Birch J, Glegola J, Manshaei S, Heide D, Dharmalingam G, Harbig J, Olona A, Behmoaras J, Dauch D, Uren AG, Zender L, Vernia S, Martínez-Barbera JP, Heikenwalder M, Withers DJ, Gil J. Guerrero A, et al. Among authors: behmoaras j. Nat Metab. 2019 Nov;1(11):1074-1088. doi: 10.1038/s42255-019-0122-z. Epub 2019 Oct 21. Nat Metab. 2019. PMID: 31799499 Free PMC article.
Adipoclast: a multinucleated fat-eating macrophage.
Olona A, Mukhopadhyay S, Hateley C, Martinez FO, Gordon S, Behmoaras J. Olona A, et al. Among authors: behmoaras j. BMC Biol. 2021 Nov 19;19(1):246. doi: 10.1186/s12915-021-01181-3. BMC Biol. 2021. PMID: 34794433 Free PMC article. Review.
Multi-tissue profiling of oxylipins reveal a conserved up-regulation of epoxide:diol ratio that associates with white adipose tissue inflammation and liver steatosis in obesity.
Hateley C, Olona A, Halliday L, Edin ML, Ko JH, Forlano R, Terra X, Lih FB, Beltrán-Debón R, Manousou P, Purkayastha S, Moorthy K, Thursz MR, Zhang G, Goldin RD, Zeldin DC, Petretto E, Behmoaras J. Hateley C, et al. Among authors: behmoaras j. EBioMedicine. 2024 Apr 26;103:105127. doi: 10.1016/j.ebiom.2024.105127. Online ahead of print. EBioMedicine. 2024. PMID: 38677183 Free PMC article.
59 results