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Phospholipase iPLA2β averts ferroptosis by eliminating a redox lipid death signal.
Sun WY, Tyurin VA, Mikulska-Ruminska K, Shrivastava IH, Anthonymuthu TS, Zhai YJ, Pan MH, Gong HB, Lu DH, Sun J, Duan WJ, Korolev S, Abramov AY, Angelova PR, Miller I, Beharier O, Mao GW, Dar HH, Kapralov AA, Amoscato AA, Hastings TG, Greenamyre TJ, Chu CT, Sadovsky Y, Bahar I, Bayır H, Tyurina YY, He RR, Kagan VE. Sun WY, et al. Among authors: beharier o. Nat Chem Biol. 2021 Apr;17(4):465-476. doi: 10.1038/s41589-020-00734-x. Epub 2021 Feb 4. Nat Chem Biol. 2021. PMID: 33542532 Free PMC article.
PLA2G6 guards placental trophoblasts against ferroptotic injury.
Beharier O, Tyurin VA, Goff JP, Guerrero-Santoro J, Kajiwara K, Chu T, Tyurina YY, St Croix CM, Wallace CT, Parry S, Parks WT, Kagan VE, Sadovsky Y. Beharier O, et al. Proc Natl Acad Sci U S A. 2020 Nov 3;117(44):27319-27328. doi: 10.1073/pnas.2009201117. Epub 2020 Oct 21. Proc Natl Acad Sci U S A. 2020. PMID: 33087576 Free PMC article.
Ferroptosis induces membrane blebbing in placental trophoblasts.
Kajiwara K, Beharier O, Chng CP, Goff JP, Ouyang Y, St Croix CM, Huang C, Kagan VE, Hsia KJ, Sadovsky Y. Kajiwara K, et al. Among authors: beharier o. J Cell Sci. 2022 Mar 1;135(5):jcs255737. doi: 10.1242/jcs.255737. Epub 2021 Apr 20. J Cell Sci. 2022. PMID: 33414166 Free PMC article.
Strikingly High Activity of 15-Lipoxygenase Towards Di-Polyunsaturated Arachidonoyl/Adrenoyl-Phosphatidylethanolamines Generates Peroxidation Signals of Ferroptotic Cell Death.
Samovich SN, Mikulska-Ruminska K, Dar HH, Tyurina YY, Tyurin VA, Souryavong AB, Kapralov AA, Amoscato AA, Beharier O, Karumanchi SA, St Croix CM, Yang X, Holman TR, VanDemark AP, Sadovsky Y, Mallampalli RK, Wenzel SE, Gu W, Bunimovich YL, Bahar I, Kagan VE, Bayir H. Samovich SN, et al. Among authors: beharier o. Angew Chem Int Ed Engl. 2024 Feb 26;63(9):e202314710. doi: 10.1002/anie.202314710. Epub 2024 Jan 17. Angew Chem Int Ed Engl. 2024. PMID: 38230815
Ovarian follicular function is not altered by SARS-CoV-2 infection or BNT162b2 mRNA COVID-19 vaccination.
Bentov Y, Beharier O, Moav-Zafrir A, Kabessa M, Godin M, Greenfield CS, Ketzinel-Gilad M, Ash Broder E, Holzer HEG, Wolf D, Oiknine-Djian E, Barghouti I, Goldman-Wohl D, Yagel S, Walfisch A, Hersko Klement A. Bentov Y, et al. Among authors: beharier o. Hum Reprod. 2021 Aug 18;36(9):2506-2513. doi: 10.1093/humrep/deab182. Hum Reprod. 2021. PMID: 34364311 Free PMC article.
57 results