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Druggable growth dependencies and tumor evolution analysis in patient-derived organoids of neuroendocrine neoplasms from multiple body sites.
Dayton TL, Alcala N, Moonen L, den Hartigh L, Geurts V, Mangiante L, Lap L, Dost AFM, Beumer J, Levy S, van Leeuwaarde RS, Hackeng WM, Samsom K, Voegele C, Sexton-Oates A, Begthel H, Korving J, Hillen L, Brosens LAA, Lantuejoul S, Jaksani S, Kok NFM, Hartemink KJ, Klomp HM, Borel Rinkes IHM, Dingemans AM, Valk GD, Vriens MR, Buikhuisen W, van den Berg J, Tesselaar M, Derks J, Speel EJ, Foll M, Fernández-Cuesta L, Clevers H. Dayton TL, et al. Among authors: begthel h. Cancer Cell. 2023 Dec 11;41(12):2083-2099.e9. doi: 10.1016/j.ccell.2023.11.007. Cancer Cell. 2023. PMID: 38086335 Free article.
The Wnt/beta-catenin pathway regulates cardiac valve formation.
Hurlstone AF, Haramis AP, Wienholds E, Begthel H, Korving J, Van Eeden F, Cuppen E, Zivkovic D, Plasterk RH, Clevers H. Hurlstone AF, et al. Among authors: begthel h. Nature. 2003 Oct 9;425(6958):633-7. doi: 10.1038/nature02028. Nature. 2003. PMID: 14534590 Free article.
Identification of stem cells in small intestine and colon by marker gene Lgr5.
Barker N, van Es JH, Kuipers J, Kujala P, van den Born M, Cozijnsen M, Haegebarth A, Korving J, Begthel H, Peters PJ, Clevers H. Barker N, et al. Among authors: begthel h. Nature. 2007 Oct 25;449(7165):1003-7. doi: 10.1038/nature06196. Epub 2007 Oct 14. Nature. 2007. PMID: 17934449
Transcription factor achaete scute-like 2 controls intestinal stem cell fate.
van der Flier LG, van Gijn ME, Hatzis P, Kujala P, Haegebarth A, Stange DE, Begthel H, van den Born M, Guryev V, Oving I, van Es JH, Barker N, Peters PJ, van de Wetering M, Clevers H. van der Flier LG, et al. Among authors: begthel h. Cell. 2009 Mar 6;136(5):903-12. doi: 10.1016/j.cell.2009.01.031. Cell. 2009. PMID: 19269367 Free article.
65 results