Beggs AD - Search Results

1

Development and Validation of a Combined Hypoxia and Immune Prognostic Classifier for Head and Neck Cancer.

Brooks JM, Menezes AN, Ibrahim M, Archer L, Lal N, Bagnall CJ, von Zeidler SV, Valentine HR, Spruce RJ, Batis N, Bryant JL, Hartley M, Kaul B, Ryan GB, Bao R, Khattri A, Lee SP, Ogbureke KUE, Middleton G, Tennant DA, Beggs AD, Deeks J, West CML, Cazier JB, Willcox BE, Seiwert TY, Mehanna H. Brooks JM, et al. Among authors: beggs ad. Clin Cancer Res. 2019 Sep 1;25(17):5315-5328. doi: 10.1158/1078-0432.CCR-18-3314. Epub 2019 Jun 10. Clin Cancer Res. 2019. PMID: 31182433

2

An immunogenomic stratification of colorectal cancer: Implications for development of targeted immunotherapy.

Lal N, Beggs AD, Willcox BE, Middleton GW. Lal N, et al. Among authors: beggs ad. Oncoimmunology. 2015 Apr 2;4(3):e976052. doi: 10.4161/2162402X.2014.976052. eCollection 2015 Mar. Oncoimmunology. 2015. PMID: 25949894 Free PMC article.

3

Methylation changes in the TFAP2E promoter region are associated with BRAF mutation and poorer overall & disease free survival in colorectal cancer.

Beggs AD, Dilworth MP, Domingo E, Midgley R, Kerr D, Tomlinson IP, Middleton GW. Beggs AD, et al. Oncoscience. 2015 Mar 23;2(5):508-16. doi: 10.18632/oncoscience.149. eCollection 2015. Oncoscience. 2015. PMID: 26097884 Free PMC article.

4

Cytomegalovirus Infection Leads to Development of High Frequencies of Cytotoxic Virus-Specific CD4+ T Cells Targeted to Vascular Endothelium.

Pachnio A, Ciaurriz M, Begum J, Lal N, Zuo J, Beggs A, Moss P. Pachnio A, et al. PLoS Pathog. 2016 Sep 8;12(9):e1005832. doi: 10.1371/journal.ppat.1005832. eCollection 2016 Sep. PLoS Pathog. 2016. PMID: 27606804 Free PMC article.

5

BRAF mutations are associated with increased iron regulatory protein-2 expression in colorectal tumorigenesis.

Horniblow RD, Bedford M, Hollingworth R, Evans S, Sutton E, Lal N, Beggs A, Iqbal TH, Tselepis C. Horniblow RD, et al. Cancer Sci. 2017 Jun;108(6):1135-1143. doi: 10.1111/cas.13234. Epub 2017 Jun 2. Cancer Sci. 2017. PMID: 28281325 Free PMC article.

6

Endothelial protein C receptor is overexpressed in colorectal cancer as a result of amplification and hypomethylation of chromosome 20q.

Lal N, Willcox CR, Beggs A, Taniere P, Shikotra A, Bradding P, Adams R, Fisher D, Middleton G, Tselepis C, Willcox BE. Lal N, et al. J Pathol Clin Res. 2017 Jul 14;3(3):155-170. doi: 10.1002/cjp2.70. eCollection 2017 Jul. J Pathol Clin Res. 2017. PMID: 28770100 Free PMC article.

7

KRAS Mutation and Consensus Molecular Subtypes 2 and 3 Are Independently Associated with Reduced Immune Infiltration and Reactivity in Colorectal Cancer.

Lal N, White BS, Goussous G, Pickles O, Mason MJ, Beggs AD, Taniere P, Willcox BE, Guinney J, Middleton GW. Lal N, et al. Among authors: beggs ad. Clin Cancer Res. 2018 Jan 1;24(1):224-233. doi: 10.1158/1078-0432.CCR-17-1090. Epub 2017 Oct 23. Clin Cancer Res. 2018. PMID: 29061646 Free PMC article.

8

Circulating tumor DNA as a biomarker and liquid biopsy in head and neck squamous cell carcinoma.

Payne K, Spruce R, Beggs A, Sharma N, Kong A, Martin T, Parmar S, Praveen P, Nankivell P, Mehanna H. Payne K, et al. Head Neck. 2018 Jul;40(7):1598-1604. doi: 10.1002/hed.25140. Epub 2018 Mar 15. Head Neck. 2018. PMID: 29542214 Review.

9

Validation of epigenetic markers to identify colitis associated cancer: Results of module 1 of the ENDCAP-C study.

Beggs AD, Mehta S, Deeks JJ, James JD, Caldwell GM, Dilworth MP, Stockton JD, Blakeway D, Pestinger V, Vince A, Taniere P, Iqbal T, Magill L, Matthews G, Morton DG; ENDCAP-C Module 1 Collaborative. Beggs AD, et al. EBioMedicine. 2019 Jan;39:265-271. doi: 10.1016/j.ebiom.2018.11.034. Epub 2018 Nov 22. EBioMedicine. 2019. PMID: 30473377 Free PMC article. Clinical Trial.

10

Mechanisms of immunogenicity in colorectal cancer.

Sillo TO, Beggs AD, Morton DG, Middleton G. Sillo TO, et al. Among authors: beggs ad. Br J Surg. 2019 Sep;106(10):1283-1297. doi: 10.1002/bjs.11204. Epub 2019 Jun 19. Br J Surg. 2019. PMID: 31216061 Free PMC article. Review.

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