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Chronically elevated branched chain amino acid levels are pro-arrhythmic.
Portero V, Nicol T, Podliesna S, Marchal GA, Baartscheer A, Casini S, Tadros R, Treur JL, Tanck MWT, Cox IJ, Probert F, Hough TA, Falcone S, Beekman L, Müller-Nurasyid M, Kastenmüller G, Gieger C, Peters A, Kääb S, Sinner MF, Blease A, Verkerk AO, Bezzina CR, Potter PK, Remme CA. Portero V, et al. Among authors: beekman l. Cardiovasc Res. 2022 Jun 22;118(7):1742-1757. doi: 10.1093/cvr/cvab207. Cardiovasc Res. 2022. PMID: 34142125 Free PMC article.
Genetically determined differences in sodium current characteristics modulate conduction disease severity in mice with cardiac sodium channelopathy.
Remme CA, Scicluna BP, Verkerk AO, Amin AS, van Brunschot S, Beekman L, Deneer VH, Chevalier C, Oyama F, Miyazaki H, Nukina N, Wilders R, Escande D, Houlgatte R, Wilde AA, Tan HL, Veldkamp MW, de Bakker JM, Bezzina CR. Remme CA, et al. Among authors: beekman l. Circ Res. 2009 Jun 5;104(11):1283-92. doi: 10.1161/CIRCRESAHA.109.194423. Epub 2009 Apr 30. Circ Res. 2009. PMID: 19407241
Mechanism of right precordial ST-segment elevation in structural heart disease: excitation failure by current-to-load mismatch.
Hoogendijk MG, Potse M, Linnenbank AC, Verkerk AO, den Ruijter HM, van Amersfoorth SC, Klaver EC, Beekman L, Bezzina CR, Postema PG, Tan HL, Reimer AG, van der Wal AC, Ten Harkel AD, Dalinghaus M, Vinet A, Wilde AA, de Bakker JM, Coronel R. Hoogendijk MG, et al. Among authors: beekman l. Heart Rhythm. 2010;7(2):238-48. doi: 10.1016/j.hrthm.2009.10.007. Epub 2009 Oct 12. Heart Rhythm. 2010. PMID: 20022821
Electrophysiologic remodeling of the left ventricle in pressure overload-induced right ventricular failure.
Hardziyenka M, Campian ME, Verkerk AO, Surie S, van Ginneken AC, Hakim S, Linnenbank AC, de Bruin-Bon HA, Beekman L, van der Plas MN, Remme CA, van Veen TA, Bresser P, de Bakker JM, Tan HL. Hardziyenka M, et al. Among authors: beekman l. J Am Coll Cardiol. 2012 Jun 12;59(24):2193-202. doi: 10.1016/j.jacc.2012.01.063. J Am Coll Cardiol. 2012. PMID: 22676940 Free article.
46 results