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High-resolution 3D imaging of fixed and cleared organoids.
Dekkers JF, Alieva M, Wellens LM, Ariese HCR, Jamieson PR, Vonk AM, Amatngalim GD, Hu H, Oost KC, Snippert HJG, Beekman JM, Wehrens EJ, Visvader JE, Clevers H, Rios AC. Dekkers JF, et al. Among authors: beekman jm. Nat Protoc. 2019 Jun;14(6):1756-1771. doi: 10.1038/s41596-019-0160-8. Epub 2019 May 3. Nat Protoc. 2019. PMID: 31053799
PPARγ as a therapeutic target in cystic fibrosis.
Dekkers JF, van der Ent CK, Kalkhoven E, Beekman JM. Dekkers JF, et al. Among authors: beekman jm. Trends Mol Med. 2012 May;18(5):283-91. doi: 10.1016/j.molmed.2012.03.004. Epub 2012 Apr 9. Trends Mol Med. 2012. PMID: 22494945 Review.
CFTR-mutation specific applications of CFTR-directed monoclonal antibodies.
van Meegen MA, Terheggen SW, Koymans KJ, Vijftigschild LA, Dekkers JF, van der Ent CK, Beekman JM. van Meegen MA, et al. Among authors: beekman jm. J Cyst Fibros. 2013 Sep;12(5):487-96. doi: 10.1016/j.jcf.2012.12.005. Epub 2013 Jan 11. J Cyst Fibros. 2013. PMID: 23317763 Free article.
A functional CFTR assay using primary cystic fibrosis intestinal organoids.
Dekkers JF, Wiegerinck CL, de Jonge HR, Bronsveld I, Janssens HM, de Winter-de Groot KM, Brandsma AM, de Jong NW, Bijvelds MJ, Scholte BJ, Nieuwenhuis EE, van den Brink S, Clevers H, van der Ent CK, Middendorp S, Beekman JM. Dekkers JF, et al. Among authors: beekman jm. Nat Med. 2013 Jul;19(7):939-45. doi: 10.1038/nm.3201. Epub 2013 Jun 2. Nat Med. 2013. PMID: 23727931
Modulation of the maladaptive stress response to manage diseases of protein folding.
Roth DM, Hutt DM, Tong J, Bouchecareilh M, Wang N, Seeley T, Dekkers JF, Beekman JM, Garza D, Drew L, Masliah E, Morimoto RI, Balch WE. Roth DM, et al. Among authors: beekman jm. PLoS Biol. 2014 Nov 18;12(11):e1001998. doi: 10.1371/journal.pbio.1001998. eCollection 2014 Nov. PLoS Biol. 2014. PMID: 25406061 Free PMC article.
A bioassay using intestinal organoids to measure CFTR modulators in human plasma.
Dekkers R, Vijftigschild LA, Vonk AM, Kruisselbrink E, de Winter-de Groot KM, Janssens HM, van der Ent CK, Beekman JM. Dekkers R, et al. Among authors: beekman jm. J Cyst Fibros. 2015 Mar;14(2):178-81. doi: 10.1016/j.jcf.2014.10.007. Epub 2014 Nov 6. J Cyst Fibros. 2015. PMID: 25467948 Free article.
128 results