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Phosphoproteomics of patient-derived xenografts identifies targets and markers associated with sensitivity and resistance to EGFR blockade in colorectal cancer.
Beekhof R, Bertotti A, Böttger F, Vurchio V, Cottino F, Zanella ER, Migliardi G, Viviani M, Grassi E, Lupo B, Henneman AA, Knol JC, Pham TV, de Goeij-de Haas R, Piersma SR, Labots M, Verheul HMW, Trusolino L, Jimenez CR. Beekhof R, et al. Sci Transl Med. 2023 Aug 16;15(709):eabm3687. doi: 10.1126/scitranslmed.abm3687. Epub 2023 Aug 16. Sci Transl Med. 2023. PMID: 37585503 Free article.
Kinase Inhibitor Treatment of Patients with Advanced Cancer Results in High Tumor Drug Concentrations and in Specific Alterations of the Tumor Phosphoproteome.
Labots M, Pham TV, Honeywell RJ, Knol JC, Beekhof R, de Goeij-de Haas R, Dekker H, Neerincx M, Piersma SR, van der Mijn JC, van der Peet DL, Meijerink MR, Peters GJ, van Grieken NCT, Jiménez CR, Verheul HMW. Labots M, et al. Among authors: beekhof r. Cancers (Basel). 2020 Feb 1;12(2):330. doi: 10.3390/cancers12020330. Cancers (Basel). 2020. PMID: 32024067 Free PMC article.
Phosphotyrosine-based Phosphoproteomics for Target Identification and Drug Response Prediction in AML Cell Lines.
van Alphen C, Cloos J, Beekhof R, Cucchi DGJ, Piersma SR, Knol JC, Henneman AA, Pham TV, van Meerloo J, Ossenkoppele GJ, Verheul HMW, Janssen JJWM, Jimenez CR. van Alphen C, et al. Among authors: beekhof r. Mol Cell Proteomics. 2020 May;19(5):884-899. doi: 10.1074/mcp.RA119.001504. Epub 2020 Feb 26. Mol Cell Proteomics. 2020. PMID: 32102969 Free PMC article.
[No title available]
[No authors listed] [No authors listed] PMID: 33451748
Candidate biomarkers for treatment benefit from sunitinib in patients with advanced renal cell carcinoma using mass spectrometry-based (phospho)proteomics.
van der Wijngaart H, Beekhof R, Knol JC, Henneman AA, de Goeij-de Haas R, Piersma SR, Pham TV, Jimenez CR, Verheul HMW, Labots M. van der Wijngaart H, et al. Among authors: beekhof r. Clin Proteomics. 2023 Nov 8;20(1):49. doi: 10.1186/s12014-023-09437-6. Clin Proteomics. 2023. PMID: 37940875 Free PMC article.
11 results