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Ancestral risk modification for multiple sclerosis susceptibility detected across the Major Histocompatibility Complex in a multi-ethnic population.
Beecham AH, Amezcua L, Chinea A, Manrique CP, Gomez L, Martinez A, Beecham GW, Patsopoulos NA, Chitnis T, Weiner HL, De Jager PL, Burchard EG, Lund BT, Fitzgerald KC, Calabresi PA, Delgado SR, Oksenberg JR, McCauley JL. Beecham AH, et al. Among authors: beecham gw. PLoS One. 2022 Dec 22;17(12):e0279132. doi: 10.1371/journal.pone.0279132. eCollection 2022. PLoS One. 2022. PMID: 36548255 Free PMC article.
A rare missense variant of CASP7 is associated with familial late-onset Alzheimer's disease.
Zhang X, Zhu C, Beecham G, Vardarajan BN, Ma Y, Lancour D, Farrell JJ, Chung J; Alzheimer's Disease Sequencing Project; Mayeux R, Haines JL, Schellenberg GD, Pericak-Vance MA, Lunetta KL, Farrer LA. Zhang X, et al. Alzheimers Dement. 2019 Mar;15(3):441-452. doi: 10.1016/j.jalz.2018.10.005. Epub 2019 Jan 3. Alzheimers Dement. 2019. PMID: 30503768 Free PMC article.
African Ancestry Individuals with Higher Educational Attainment Are Resilient to Alzheimer's Disease Measured by pTau181.
Rajabli F, Seixas AA, Akgun B, Adams LD, Inciute J, Hamilton KL, Whithead PG, Konidari I, Gu T, Arvizu J, Golightly CG, Starks TD, Laux R, Byrd GS, Haines JL, Beecham GW, Griswold AJ, Vance JM, Cuccaro ML, Pericak-Vance MA. Rajabli F, et al. Among authors: beecham gw. J Alzheimers Dis. 2024;98(1):221-229. doi: 10.3233/JAD-231116. J Alzheimers Dis. 2024. PMID: 38393909 Free PMC article.
Prediction of neuropathologic lesions from clinical data.
Phongpreecha T, Cholerton B, Bukhari S, Chang AL, De Francesco D, Thuraiappah M, Godrich D, Perna A, Becker MG, Ravindra NG, Espinosa C, Kim Y, Berson E, Mataraso S, Sha SJ, Fox EJ, Montine KS, Baker LD, Craft S, White L, Poston KL, Beecham G, Aghaeepour N, Montine TJ. Phongpreecha T, et al. Alzheimers Dement. 2023 Jul;19(7):3005-3018. doi: 10.1002/alz.12921. Epub 2023 Jan 21. Alzheimers Dement. 2023. PMID: 36681388
Generalizability of Tau and Amyloid Plasma Biomarkers in Alzheimer's Disease Cohorts of Diverse Genetic Ancestries.
Griswold AJ, Rajabli F, Gu T, Arvizu J, Golightly CG, Whitehead PL, Hamilton-Nelson KL, Adams LD, Sanchez JJ, Mena PR, Starks TD, Illanes-Manrique M, Silva C, Bush WS, Cuccaro ML, Vance JM, Cornejo-Olivas MR, Feliciano-Astacio BE, Byrd GS, Beecham GW, Haines JL, Pericak-Vance MA. Griswold AJ, et al. Among authors: beecham gw. medRxiv [Preprint]. 2024 Apr 12:2024.04.10.24305617. doi: 10.1101/2024.04.10.24305617. medRxiv. 2024. PMID: 38645114 Free PMC article. Preprint.
Whole genome-wide sequence analysis of long-lived families (Long-Life Family Study) identifies MTUS2 gene associated with late-onset Alzheimer's disease.
Xicota L, Cosentino S, Vardarajan B, Mayeux R, Perls TT, Andersen SL, Zmuda JM, Thyagarajan B, Yashin A, Wojczynski MK, Krinsky-McHale S, Handen BL, Christian BT, Head E, Mapstone ME, Schupf N, Lee JH, Barral S; Long‐Life Family Study (LLFS); Alzheimer's Disease Genetic Consortium (ADGC); Alzheimer's Biomarkers Consortium‐Down Syndrome (ABC‐DS). Xicota L, et al. Alzheimers Dement. 2024 Apr;20(4):2670-2679. doi: 10.1002/alz.13718. Epub 2024 Feb 21. Alzheimers Dement. 2024. PMID: 38380866 Free PMC article.
Genetic analyses in multiplex families confirms chromosome 5q35 as a risk locus for Alzheimer's Disease in individuals of African Ancestry.
Nuytemans K, Rajabli F, Jean-Francois M, Kurup JT, Adams LD, Starks TD, Whitehead PL, Kunkle BW, Caban-Holt A, Haines JL, Cuccaro ML, Vance JM, Byrd GS, Beecham GW, Reitz C, Pericak-Vance MA; NIA-LOAD Family-Based Study; Alzheimer’s Disease Sequencing Project. Nuytemans K, et al. Among authors: beecham gw. Neurobiol Aging. 2024 Jan;133:125-133. doi: 10.1016/j.neurobiolaging.2023.10.010. Epub 2023 Oct 31. Neurobiol Aging. 2024. PMID: 37952397 Free article.
Extended genome-wide association study employing the African Genome Resources Panel identifies novel susceptibility loci for Alzheimer's Disease in individuals of African ancestry.
Ray NR, Kunkle BW, Hamilton-Nelson K, Kurup JT, Rajabli F, Cosacak MI, Kizil C, Jean-Francois M, Cuccaro M, Reyes-Dumeyer D, Cantwell L, Kuzma A, Vance JM, Gao S, Hendrie HC, Baiyewu O, Ogunniyi A, Akinyemi RO; Alzheimer’s Disease Genetics Consortium; Lee WP, Martin ER, Wang LS, Beecham GW, Bush WS, Farrer LA, Haines JL, Byrd GS, Schellenberg GD, Mayeux R, Pericak-Vance MA, Reitz C. Ray NR, et al. Among authors: beecham gw. medRxiv [Preprint]. 2023 Aug 29:2023.08.29.23294774. doi: 10.1101/2023.08.29.23294774. medRxiv. 2023. PMID: 37693582 Free PMC article. Preprint.
Neuropsychiatric features in a multi-ethnic population with Alzheimer disease and mild cognitive impairment.
Celis K, Zaman A, Adams LD, Gardner O, Farid R, Starks TD, Lacroix FC, Hamilton-Nelson K, Mena P, Tejada S, Laux R, Song YE, Caban-Holt A, Feliciano-Astacio B, Vance JM, Haines JL, Byrd GS, Beecham GW, Pericak-Vance MA, Cuccaro ML. Celis K, et al. Among authors: beecham gw. Int J Geriatr Psychiatry. 2023 Sep;38(9):e5992. doi: 10.1002/gps.5992. Int J Geriatr Psychiatry. 2023. PMID: 37655494
121 results