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A2B adenosine receptor antagonists: Design, synthesis and biological evaluation of novel xanthine derivatives.
Basu S, Barawkar DA, Ramdas V, Waman Y, Patel M, Panmand A, Kumar S, Thorat S, Bonagiri R, Jadhav D, Mukhopadhyay P, Prasad V, Reddy BS, Goswami A, Chaturvedi S, Menon S, Quraishi A, Ghosh I, Dusange S, Paliwal S, Kulkarni A, Karande V, Thakre R, Bedse G, Rouduri S, Gundu J, Palle VP, Chugh A, Mookhtiar KA. Basu S, et al. Among authors: bedse g. Eur J Med Chem. 2017 Feb 15;127:986-996. doi: 10.1016/j.ejmech.2016.11.007. Epub 2016 Nov 8. Eur J Med Chem. 2017. PMID: 27842891
Design and synthesis of novel, potent and selective hypoxanthine analogs as adenosine A1 receptor antagonists and their biological evaluation.
Koul S, Ramdas V, Barawkar DA, Waman YB, Prasad N, Madadi SK, Shejul YD, Bonagiri R, Basu S, Menon S, Reddy SB, Chaturvedi S, Chennamaneni SR, Bedse G, Thakare R, Gundu J, Chaudhary S, De S, Meru AV, Palle V, Chugh A, Mookhtiar KA. Koul S, et al. Among authors: bedse g. Bioorg Med Chem. 2017 Mar 15;25(6):1963-1975. doi: 10.1016/j.bmc.2017.02.029. Epub 2017 Feb 16. Bioorg Med Chem. 2017. PMID: 28238512
Pivekimab sunirine (IMGN632), a novel CD123-targeting antibody-drug conjugate, in relapsed or refractory acute myeloid leukaemia: a phase 1/2 study.
Daver NG, Montesinos P, DeAngelo DJ, Wang ES, Papadantonakis N, Todisco E, Sweet KL, Pemmaraju N, Lane AA, Torres-Miñana L, Thompson JE, Konopleva MY, Sloss CM, Watkins K, Bedse G, Du Y, Malcolm KE, Zweidler-McKay PA, Kantarjian HM. Daver NG, et al. Among authors: bedse g. Lancet Oncol. 2024 Mar;25(3):388-399. doi: 10.1016/S1470-2045(23)00674-5. Lancet Oncol. 2024. PMID: 38423051 Clinical Trial.
Targeting diacylglycerol lipase reduces alcohol consumption in preclinical models.
Winters ND, Bedse G, Astafyev AA, Patrick TA, Altemus M, Morgan AJ, Mukerjee S, Johnson KD, Mahajan VR, Uddin MJ, Kingsley PJ, Centanni SW, Siciliano CA, Samuels DC, Marnett LJ, Winder DG, Patel S. Winters ND, et al. Among authors: bedse g. J Clin Invest. 2021 Jul 22;131(17):e146861. doi: 10.1172/JCI146861. Online ahead of print. J Clin Invest. 2021. PMID: 34292886 Free PMC article.
28 results