Bedoya LM - Search Results

1

Exploring the HIV-1 Rev Recognition Element (RRE)-Rev Inhibitory Capacity and Antiretroviral Action of Benfluron Analogs.

Chumillas S, Loharch S, Beltrán M, Szewczyk MP, Bernal S, Puertas MC, Martinez-Picado J, Alcamí J, Bedoya LM, Marchán V, Gallego J. Chumillas S, et al. Among authors: bedoya lm. Molecules. 2023 Oct 11;28(20):7031. doi: 10.3390/molecules28207031. Molecules. 2023. PMID: 37894510 Free PMC article.

2

Bioavailable inhibitors of HIV-1 RNA biogenesis identified through a Rev-based screen.

Prado S, Beltrán M, Coiras M, Bedoya LM, Alcamí J, Gallego J. Prado S, et al. Among authors: bedoya lm. Biochem Pharmacol. 2016 May 1;107:14-28. doi: 10.1016/j.bcp.2016.02.007. Epub 2016 Feb 17. Biochem Pharmacol. 2016. PMID: 26896646

3

A small-molecule inhibitor of HIV-1 Rev function detected by a diversity screen based on RRE-Rev interference.

Prado S, Beltrán M, Moreno Á, Bedoya LM, Alcamí J, Gallego J. Prado S, et al. Among authors: bedoya lm. Biochem Pharmacol. 2018 Oct;156:68-77. doi: 10.1016/j.bcp.2018.07.040. Epub 2018 Jul 31. Biochem Pharmacol. 2018. PMID: 30071201

4

Nucleic acid recognition and antiviral activity of 1,4-substituted terphenyl compounds mimicking all faces of the HIV-1 Rev protein positively-charged α-helix.

Medina-Trillo C, Sedgwick DM, Herrera L, Beltrán M, Moreno Á, Barrio P, Bedoya LM, Alcamí J, Fustero S, Gallego J. Medina-Trillo C, et al. Among authors: bedoya lm. Sci Rep. 2020 Apr 28;10(1):7190. doi: 10.1038/s41598-020-64120-2. Sci Rep. 2020. PMID: 32346097 Free PMC article.

5

Novel HIV-1 RNA biogenesis inhibitors identified by virtual pharmacophore-based screening.

Simba-Lahuasi Á, Alcamí J, Beltrán M, Bedoya LM, Gallego J. Simba-Lahuasi Á, et al. Among authors: bedoya lm. Biochem Pharmacol. 2023 Sep;215:115734. doi: 10.1016/j.bcp.2023.115734. Epub 2023 Aug 6. Biochem Pharmacol. 2023. PMID: 37549794

6

Structure-based design of an RNA-binding p-terphenylene scaffold that inhibits HIV-1 Rev protein function.

González-Bulnes L, Ibáñez I, Bedoya LM, Beltrán M, Catalán S, Alcamí J, Fustero S, Gallego J. González-Bulnes L, et al. Among authors: bedoya lm. Angew Chem Int Ed Engl. 2013 Dec 9;52(50):13405-9. doi: 10.1002/anie.201306665. Epub 2013 Nov 8. Angew Chem Int Ed Engl. 2013. PMID: 24214163 No abstract available.

7

Neoflavonoids as Inhibitors of HIV-1 Replication by Targeting the Tat and NF-κB Pathways.

Olmedo DA, López-Pérez JL, Del Olmo E, Bedoya LM, Sancho R, Alcamí J, Muñoz E, Feliciano AS, Gupta MP. Olmedo DA, et al. Among authors: bedoya lm. Molecules. 2017 Feb 19;22(2):321. doi: 10.3390/molecules22020321. Molecules. 2017. PMID: 28218730 Free PMC article.

8

Promiscuous, Multi-Target Lupane-Type Triterpenoids Inhibits Wild Type and Drug Resistant HIV-1 Replication Through the Interference With Several Targets.

Bedoya LM, Beltrán M, García-Pérez J, Obregón-Calderón P, Callies O, Jímenez IA, Bazzocchi IL, Alcamí J. Bedoya LM, et al. Front Pharmacol. 2018 Apr 18;9:358. doi: 10.3389/fphar.2018.00358. eCollection 2018. Front Pharmacol. 2018. PMID: 29720939 Free PMC article.

9

Withanolide-Type Steroids from Physalis nicandroides Inhibit HIV Transcription.

Taddeo VA, Núñez MJ, Beltrán M, Castillo UG, Menjívar J, Jiménez IA, Alcamí J, Bedoya LM, Bazzocchi IL. Taddeo VA, et al. Among authors: bedoya lm. J Nat Prod. 2021 Oct 22;84(10):2717-2726. doi: 10.1021/acs.jnatprod.1c00637. Epub 2021 Sep 22. J Nat Prod. 2021. PMID: 34549952 Free PMC article.

10

4-Phenylcoumarins as HIV transcription inhibitors.

Bedoya LM, Beltrán M, Sancho R, Olmedo DA, Sánchez-Palomino S, del Olmo E, López-Pérez JL, Muñoz E, San Feliciano A, Alcamí J. Bedoya LM, et al. Bioorg Med Chem Lett. 2005 Oct 15;15(20):4447-50. doi: 10.1016/j.bmcl.2005.07.041. Bioorg Med Chem Lett. 2005. PMID: 16137881

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