Bedewitz M - Search Results

1

Rapid biosensor development using plant hormone receptors as reprogrammable scaffolds.

Beltrán J, Steiner PJ, Bedewitz M, Wei S, Peterson FC, Li Z, Hughes BE, Hartley Z, Robertson NR, Medina-Cucurella AV, Baumer ZT, Leonard AC, Park SY, Volkman BF, Nusinow DA, Zhong W, Wheeldon I, Cutler SR, Whitehead TA. Beltrán J, et al. Among authors: bedewitz m. Nat Biotechnol. 2022 Dec;40(12):1855-1861. doi: 10.1038/s41587-022-01364-5. Epub 2022 Jun 20. Nat Biotechnol. 2022. PMID: 35726092 Free PMC article.

2

An Automated Data-Driven Pipeline for Improving Heterologous Enzyme Expression.

Wrenbeck EE, Bedewitz MA, Klesmith JR, Noshin S, Barry CS, Whitehead TA. Wrenbeck EE, et al. Among authors: bedewitz ma. ACS Synth Biol. 2019 Mar 15;8(3):474-481. doi: 10.1021/acssynbio.8b00486. Epub 2019 Feb 8. ACS Synth Biol. 2019. PMID: 30721031 Free PMC article.

3

A Closed Form Model for Molecular Ratchet-Type Chemically Induced Dimerization Modules.

Steiner PJ, Swift SD, Bedewitz M, Wheeldon I, Cutler SR, Nusinow DA, Whitehead TA. Steiner PJ, et al. Among authors: bedewitz m. Biochemistry. 2023 Jan 17;62(2):281-291. doi: 10.1021/acs.biochem.2c00172. Epub 2022 Jun 8. Biochemistry. 2023. PMID: 35675717

4

Metabolomics-guided discovery of cytochrome P450s involved in pseudotropine-dependent biosynthesis of modified tropane alkaloids.

Sadre R, Anthony TM, Grabar JM, Bedewitz MA, Jones AD, Barry CS. Sadre R, et al. Among authors: bedewitz ma. Nat Commun. 2022 Jul 2;13(1):3832. doi: 10.1038/s41467-022-31653-1. Nat Commun. 2022. PMID: 35780230 Free PMC article.

5

Tropinone synthesis via an atypical polyketide synthase and P450-mediated cyclization.

Bedewitz MA, Jones AD, D'Auria JC, Barry CS. Bedewitz MA, et al. Nat Commun. 2018 Dec 11;9(1):5281. doi: 10.1038/s41467-018-07671-3. Nat Commun. 2018. PMID: 30538251 Free PMC article.

6

A root-expressed L-phenylalanine:4-hydroxyphenylpyruvate aminotransferase is required for tropane alkaloid biosynthesis in Atropa belladonna.

Bedewitz MA, Góngora-Castillo E, Uebler JB, Gonzales-Vigil E, Wiegert-Rininger KE, Childs KL, Hamilton JP, Vaillancourt B, Yeo YS, Chappell J, DellaPenna D, Jones AD, Buell CR, Barry CS. Bedewitz MA, et al. Plant Cell. 2014 Sep;26(9):3745-62. doi: 10.1105/tpc.114.130534. Epub 2014 Sep 16. Plant Cell. 2014. PMID: 25228340 Free PMC article.

7

Redirecting tropane alkaloid metabolism reveals pyrrolidine alkaloid diversity in Atropa belladonna.

Parks HM, Cinelli MA, Bedewitz MA, Grabar JM, Hurney SM, Walker KD, Jones AD, Barry CS. Parks HM, et al. Among authors: bedewitz ma. New Phytol. 2023 Mar;237(5):1810-1825. doi: 10.1111/nph.18651. Epub 2022 Dec 18. New Phytol. 2023. PMID: 36451537 Free PMC article.

8

GMMA Can Stabilize Proteins Across Different Functional Constraints.

Daffern N, Johansson KE, Baumer ZT, Robertson NR, Woojuh J, Bedewitz MA, Davis Z, Wheeldon I, Cutler SR, Lindorff-Larsen K, Whitehead TA. Daffern N, et al. Among authors: bedewitz ma. J Mol Biol. 2024 Apr 23;436(11):168586. doi: 10.1016/j.jmb.2024.168586. Online ahead of print. J Mol Biol. 2024. PMID: 38663544

9

High-Performance Cannabinoid Sensor Empowered by Plant Hormone Receptors and Antifouling Magnetic Nanorods.

Li Z, Shen Y, Beltrán J, Tian H, Bedewitz M, Wheeldon I, Whitehead TA, Cutler SR, Zhong W. Li Z, et al. Among authors: bedewitz m. ACS Sens. 2023 Oct 27;8(10):3914-3922. doi: 10.1021/acssensors.3c01488. Epub 2023 Sep 22. ACS Sens. 2023. PMID: 37737572

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