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BCL-2-family protein tBID can act as a BAX-like effector of apoptosis.
Flores-Romero H, Hohorst L, John M, Albert MC, King LE, Beckmann L, Szabo T, Hertlein V, Luo X, Villunger A, Frenzel LP, Kashkar H, Garcia-Saez AJ. Flores-Romero H, et al. Among authors: beckmann l. EMBO J. 2022 Dec 17;41(2):e108690. doi: 10.15252/embj.2021108690. Epub 2021 Dec 21. EMBO J. 2022. PMID: 34931711 Free PMC article.
Deregulation and epigenetic modification of BCL2-family genes cause resistance to venetoclax in hematologic malignancies.
Thomalla D, Beckmann L, Grimm C, Oliverio M, Meder L, Herling CD, Nieper P, Feldmann T, Merkel O, Lorsy E, da Palma Guerreiro A, von Jan J, Kisis I, Wasserburger E, Claasen J, Faitschuk-Meyer E, Altmüller J, Nürnberg P, Yang TP, Lienhard M, Herwig R, Kreuzer KA, Pallasch CP, Büttner R, Schäfer SC, Hartley J, Abken H, Peifer M, Kashkar H, Knittel G, Eichhorst B, Ullrich RT, Herling M, Reinhardt HC, Hallek M, Schweiger MR, Frenzel LP. Thomalla D, et al. Among authors: beckmann l. Blood. 2022 Nov 17;140(20):2113-2126. doi: 10.1182/blood.2021014304. Blood. 2022. PMID: 35704690 Free PMC article.
Hypoxia-induced p38 MAPK activation reduces Mcl-1 expression and facilitates sensitivity towards BH3 mimetics in chronic lymphocytic leukemia.
Huelsemann MF, Patz M, Beckmann L, Brinkmann K, Otto T, Fandrey J, Becker HJ, Theurich S, von Bergwelt-Baildon M, Pallasch CP, Zahedi RP, Kashkar H, Reinhardt HC, Hallek M, Wendtner CM, Frenzel LP. Huelsemann MF, et al. Among authors: beckmann l. Leukemia. 2015 Apr;29(4):981-4. doi: 10.1038/leu.2014.320. Epub 2014 Nov 7. Leukemia. 2015. PMID: 25376373 No abstract available.
MARCKS affects cell motility and response to BTK inhibitors in CLL.
Beckmann L, Berg V, Dickhut C, Sun C, Merkel O, Bloehdorn J, Robrecht S, Seifert M, da Palma Guerreiro A, Claasen J, Loroch S, Oliverio M, Underbayev C, Vaughn L, Thomalla D, Hülsemann MF, Tausch E, Fischer K, Fink AM, Eichhorst B, Sickmann A, Wendtner CM, Stilgenbauer S, Hallek M, Wiestner A, Zahedi RP, Frenzel LP. Beckmann L, et al. Blood. 2021 Aug 19;138(7):544-556. doi: 10.1182/blood.2020009165. Blood. 2021. PMID: 33735912 Free PMC article.
Multicenter development of a PET-based risk assessment tool for product-specific outcome prediction in large B-cell lymphoma patients undergoing CAR T-cell therapy.
Voltin CA, Paccagnella A, Winkelmann M, Heger JM, Casadei B, Beckmann L, Herrmann K, Dekorsy FJ, Kutsch N, Borchmann P, Fanti S, Kunz WG, Subklewe M, Kobe C, Zinzani PL, Stelljes M, Roth KS, Drzezga A, Noppeney R, Rahbar K, Reinhardt HC, von Tresckow B, Seifert R, Albring JC, Blumenberg V, Farolfi A, Flossdorf S, Gödel P, Hanoun C. Voltin CA, et al. Among authors: beckmann l. Eur J Nucl Med Mol Imaging. 2024 Apr;51(5):1361-1370. doi: 10.1007/s00259-023-06554-0. Epub 2023 Dec 20. Eur J Nucl Med Mol Imaging. 2024. PMID: 38114616 Free PMC article.
Effect of factor XI inhibition on tumor cell-induced coagulation activation.
Mäder J, Rolling CC, Voigtländer M, Schulenkorf A, Lehr C, Regenhardt J, Bokemeyer C, Beckmann L, Langer F. Mäder J, et al. Among authors: beckmann l. J Thromb Haemost. 2024 Jan;22(1):199-212. doi: 10.1016/j.jtha.2023.09.015. Epub 2023 Sep 24. J Thromb Haemost. 2024. PMID: 37751848
139 results