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Resolving sepsis-induced immunoparalysis via trained immunity by targeting interleukin-4 to myeloid cells.
Nat Biomed Eng. 2023 Sep;7(9):1097-1112. doi: 10.1038/s41551-023-01050-0. Epub 2023 Jun 8.
Nat Biomed Eng. 2023.
PMID: 37291433
Free PMC article.
Inhibition of CSF-1R and IL-6R prevents conversion of cDC2s into immune incompetent tumor-induced DC3s boosting DC-driven therapy potential.
Becker AMD, Decker AH, Flórez-Grau G, Bakdash G, Röring RJ, Stelloo S, Vermeulen M, Piet B, Aarntzen EHJG, Verdoes M, de Vries IJM.
Becker AMD, et al.
Cell Rep Med. 2024 Feb 20;5(2):101386. doi: 10.1016/j.xcrm.2023.101386. Epub 2024 Jan 18.
Cell Rep Med. 2024.
PMID: 38242119
Free PMC article.
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The tumour microenvironment shapes dendritic cell plasticity in a human organotypic melanoma culture.
Di Blasio S, van Wigcheren GF, Becker A, van Duffelen A, Gorris M, Verrijp K, Stefanini I, Bakker GJ, Bloemendal M, Halilovic A, Vasaturo A, Bakdash G, Hato SV, de Wilt JHW, Schalkwijk J, de Vries IJM, Textor JC, van den Bogaard EH, Tazzari M, Figdor CG.
Di Blasio S, et al.
Nat Commun. 2020 Jun 2;11(1):2749. doi: 10.1038/s41467-020-16583-0.
Nat Commun. 2020.
PMID: 32488012
Free PMC article.
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Efficient targeting of NY-ESO-1 tumor antigen to human cDC1s by lymphotactin results in cross-presentation and antigen-specific T cell expansion.
Le Gall C, Cammarata A, de Haas L, Ramos-Tomillero I, Cuenca-Escalona J, Schouren K, Wijfjes Z, Becker AMD, Bödder J, Dölen Y, de Vries IJM, Figdor CG, Flórez-Grau G, Verdoes M.
Le Gall C, et al. Among authors: becker amd.
J Immunother Cancer. 2022 Apr;10(4):e004309. doi: 10.1136/jitc-2021-004309.
J Immunother Cancer. 2022.
PMID: 35428705
Free PMC article.
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cDC2 plasticity and acquisition of a DC3-like phenotype mediated by IL-6 and PGE2 in a patient-derived colorectal cancer organoids model.
Subtil B, van der Hoorn IAE, Cuenca-Escalona J, Becker AMD, Alvarez-Begue M, Iyer KK, Janssen J, van Oorschot T, Poel D, Gorris MAJ, van den Dries K, Cambi A, Tauriello DVF, de Vries IJM.
Subtil B, et al. Among authors: becker amd.
Eur J Immunol. 2024 Mar 21:e2350891. doi: 10.1002/eji.202350891. Online ahead of print.
Eur J Immunol. 2024.
PMID: 38509863
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Functional diversification of hybridoma-produced antibodies by CRISPR/HDR genomic engineering.
van der Schoot JMS, Fennemann FL, Valente M, Dolen Y, Hagemans IM, Becker AMD, Le Gall CM, van Dalen D, Cevirgel A, van Bruggen JAC, Engelfriet M, Caval T, Bentlage AEH, Fransen MF, Nederend M, Leusen JHW, Heck AJR, Vidarsson G, Figdor CG, Verdoes M, Scheeren FA.
van der Schoot JMS, et al. Among authors: becker amd.
Sci Adv. 2019 Aug 28;5(8):eaaw1822. doi: 10.1126/sciadv.aaw1822. eCollection 2019 Aug.
Sci Adv. 2019.
PMID: 31489367
Free PMC article.
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