Beck-Sickinger AG - Search Results

1

Photoinduced receptor confinement drives ligand-independent GPCR signaling.

Sánchez MF, Els-Heindl S, Beck-Sickinger AG, Wieneke R, Tampé R. Sánchez MF, et al. Science. 2021 Mar 26;371(6536):eabb7657. doi: 10.1126/science.abb7657. Epub 2021 Feb 25. Science. 2021. PMID: 33632896

2

Biophysical methods to study ligand-receptor interactions of neuropeptide Y.

Bettio A, Beck-Sickinger AG. Bettio A, et al. Biopolymers. 2001;60(6):420-37. doi: 10.1002/1097-0282(2001)60:6<420::AID-BIP10183>3.0.CO;2-W. Biopolymers. 2001. PMID: 12209475 Review.

3

Automated solid-phase peptide synthesis to obtain therapeutic peptides.

Mäde V, Els-Heindl S, Beck-Sickinger AG. Mäde V, et al. Beilstein J Org Chem. 2014 May 22;10:1197-212. doi: 10.3762/bjoc.10.118. eCollection 2014. Beilstein J Org Chem. 2014. PMID: 24991269 Free PMC article. Review.

4

High metabolic in vivo stability and bioavailability of a palmitoylated ghrelin receptor ligand assessed by mass spectrometry.

Kostelnik KB, Els-Heindl S, Klöting N, Baumann S, von Bergen M, Beck-Sickinger AG. Kostelnik KB, et al. Bioorg Med Chem. 2015 Jul 15;23(14):3925-32. doi: 10.1016/j.bmc.2014.12.008. Epub 2014 Dec 10. Bioorg Med Chem. 2015. PMID: 25541202

5

Integrating solid-state NMR and computational modeling to investigate the structure and dynamics of membrane-associated ghrelin.

Vortmeier G, DeLuca SH, Els-Heindl S, Chollet C, Scheidt HA, Beck-Sickinger AG, Meiler J, Huster D. Vortmeier G, et al. PLoS One. 2015 Mar 24;10(3):e0122444. doi: 10.1371/journal.pone.0122444. eCollection 2015. PLoS One. 2015. PMID: 25803439 Free PMC article.

6

Rational design of dual peptides targeting ghrelin and Y2 receptors to regulate food intake and body weight.

Kilian TM, Klöting N, Bergmann R, Els-Heindl S, Babilon S, Clément-Ziza M, Zhang Y, Beck-Sickinger AG, Chollet C. Kilian TM, et al. J Med Chem. 2015 May 28;58(10):4180-93. doi: 10.1021/jm501702q. Epub 2015 May 7. J Med Chem. 2015. PMID: 25905598

7

Bioorthogonal Labeling of Ghrelin Receptor to Facilitate Studies of Ligand-Dependent Conformational Dynamics.

Park M, Sivertsen BB, Els-Heindl S, Huber T, Holst B, Beck-Sickinger AG, Schwartz TW, Sakmar TP. Park M, et al. Chem Biol. 2015 Nov 19;22(11):1431-1436. doi: 10.1016/j.chembiol.2015.09.014. Epub 2015 Nov 5. Chem Biol. 2015. PMID: 26548612

8

C-terminus of a hexapeptidic ghrelin receptor inverse agonist can switch peptide behavior from inverse agonism to agonism.

Els-Heindl S, Bellmann-Sickert K, Beck-Sickinger AG. Els-Heindl S, et al. Biopolymers. 2016 Jan;106(1):101-8. doi: 10.1002/bip.22768. Biopolymers. 2016. PMID: 26566778

9

Peptide mini-scaffold facilitates JNK3 activation in cells.

Zhan X, Stoy H, Kaoud TS, Perry NA, Chen Q, Perez A, Els-Heindl S, Slagis JV, Iverson TM, Beck-Sickinger AG, Gurevich EV, Dalby KN, Gurevich VV. Zhan X, et al. Sci Rep. 2016 Feb 12;6:21025. doi: 10.1038/srep21025. Sci Rep. 2016. PMID: 26868142 Free PMC article.

10

Adrenomedullin 2.0: Adjusting Key Levers for Metabolic Stability.

Schönauer R, Els-Heindl S, Fischer JP, Köbberling J, Riedl B, Beck-Sickinger AG. Schönauer R, et al. J Med Chem. 2016 Jun 23;59(12):5695-705. doi: 10.1021/acs.jmedchem.6b00126. Epub 2016 Jun 6. J Med Chem. 2016. PMID: 27166982

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