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Selective modulation of the glucocorticoid receptor can distinguish between transrepression of NF-κB and AP-1.
De Bosscher K, Beck IM, Dejager L, Bougarne N, Gaigneaux A, Chateauvieux S, Ratman D, Bracke M, Tavernier J, Vanden Berghe W, Libert C, Diederich M, Haegeman G. De Bosscher K, et al. Among authors: beck im. Cell Mol Life Sci. 2014 Jan;71(1):143-63. doi: 10.1007/s00018-013-1367-4. Epub 2013 Jun 20. Cell Mol Life Sci. 2014. PMID: 23784308 Free PMC article.
Compound A, a selective glucocorticoid receptor modulator, enhances heat shock protein Hsp70 gene promoter activation.
Beck IM, Drebert ZJ, Hoya-Arias R, Bahar AA, Devos M, Clarisse D, Desmet S, Bougarne N, Ruttens B, Gossye V, Denecker G, Lievens S, Bracke M, Tavernier J, Declercq W, Gevaert K, Vanden Berghe W, Haegeman G, De Bosscher K. Beck IM, et al. PLoS One. 2013 Jul 30;8(7):e69115. doi: 10.1371/journal.pone.0069115. Print 2013. PLoS One. 2013. PMID: 23935933 Free PMC article.
Pharmacological levels of Withaferin A (Withania somnifera) trigger clinically relevant anticancer effects specific to triple negative breast cancer cells.
Szarc vel Szic K, Op de Beeck K, Ratman D, Wouters A, Beck IM, Declerck K, Heyninck K, Fransen E, Bracke M, De Bosscher K, Lardon F, Van Camp G, Vanden Berghe W. Szarc vel Szic K, et al. Among authors: beck im. PLoS One. 2014 Feb 3;9(2):e87850. doi: 10.1371/journal.pone.0087850. eCollection 2014. PLoS One. 2014. PMID: 24498382 Free PMC article.
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