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Blockade of A2A receptors potently suppresses the metastasis of CD73+ tumors.
Beavis PA, Divisekera U, Paget C, Chow MT, John LB, Devaud C, Dwyer K, Stagg J, Smyth MJ, Darcy PK. Beavis PA, et al. Proc Natl Acad Sci U S A. 2013 Sep 3;110(36):14711-6. doi: 10.1073/pnas.1308209110. Epub 2013 Aug 20. Proc Natl Acad Sci U S A. 2013. PMID: 23964122 Free PMC article.
CD73-deficient mice are resistant to carcinogenesis.
Stagg J, Beavis PA, Divisekera U, Liu MC, Möller A, Darcy PK, Smyth MJ. Stagg J, et al. Among authors: beavis pa. Cancer Res. 2012 May 1;72(9):2190-6. doi: 10.1158/0008-5472.CAN-12-0420. Epub 2012 Mar 6. Cancer Res. 2012. PMID: 22396496
A2A blockade enhances anti-metastatic immune responses.
Beavis PA, Milenkovski N, Stagg J, Smyth MJ, Darcy PK. Beavis PA, et al. Oncoimmunology. 2013 Dec 1;2(12):e26705. doi: 10.4161/onci.26705. Epub 2013 Oct 22. Oncoimmunology. 2013. PMID: 24575377 Free PMC article.
CD3bright signals on γδ T cells identify IL-17A-producing Vγ6Vδ1+ T cells.
Paget C, Chow MT, Gherardin NA, Beavis PA, Uldrich AP, Duret H, Hassane M, Souza-Fonseca-Guimaraes F, Mogilenko DA, Staumont-Sallé D, Escalante NK, Hill GR, Neeson P, Ritchie DS, Dombrowicz D, Mallevaey T, Trottein F, Belz GT, Godfrey DI, Smyth MJ. Paget C, et al. Among authors: beavis pa. Immunol Cell Biol. 2015 Feb;93(2):198-212. doi: 10.1038/icb.2014.94. Epub 2014 Nov 11. Immunol Cell Biol. 2015. PMID: 25385067 Free article.
Cross-talk between tumors can affect responses to therapy.
Devaud C, John LB, Westwood JA, Yong CS, Beavis PA, Schwendener RA, Darcy PK, Kershaw MH. Devaud C, et al. Among authors: beavis pa. Oncoimmunology. 2015 Jun 17;4(7):e975572. doi: 10.4161/2162402X.2014.975572. eCollection 2015 Jul. Oncoimmunology. 2015. PMID: 26140251 Free PMC article.
80 results